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Dehydrozaluzanin C, a novel type of anti-bacterial agent which targets transporting proteins, Opp and OpuC.

作者信息

Qin Xiangyang, Xu Jinmei, Yin Dandan, Feng Fan, Zeng Xianfei, Niu Bing, Hu Xingbin

机构信息

Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an, Shaanxi 710032, PR China.

Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, PR China.

出版信息

Genes Dis. 2021 Dec 9;9(4):830-832. doi: 10.1016/j.gendis.2021.11.009. eCollection 2022 Jul.

DOI:10.1016/j.gendis.2021.11.009
PMID:35685461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9170607/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e2/9170607/87a2da8ae35e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e2/9170607/87a2da8ae35e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e2/9170607/87a2da8ae35e/gr1.jpg

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Science. 2021 Jun 11;372(6547):1169-1175. doi: 10.1126/science.abd8377.
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Structural insight into the ATP-driven exporter of virulent peptide toxins.结构洞察致病毒素肽的 ATP 驱动型外排泵。
Sci Adv. 2020 Sep 30;6(40). doi: 10.1126/sciadv.abb8219. Print 2020 Sep.
3
Management of Osmoprotectant Uptake Hierarchy in via a SigB-Dependent Antisense RNA.通过依赖SigB的反义RNA对渗透压保护剂摄取层级的管理
Front Microbiol. 2020 Apr 21;11:622. doi: 10.3389/fmicb.2020.00622. eCollection 2020.
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Drugs for bad bugs: confronting the challenges of antibacterial discovery.对抗耐药菌的药物：应对抗菌药物研发的挑战
Nat Rev Drug Discov. 2007 Jan;6(1):29-40. doi: 10.1038/nrd2201. Epub 2006 Dec 8.