Mi Junjie, Han Xiaofang, Wang Rong, Ma Ruijun, Zhao Danyu
Digestive Endoscopy Center, Shanxi Provincial People's Hospital, Taiyuan, China.
Reproductive Medicine, Shanxi Provincial People's Hospital, Taiyuan, China.
Int J Clin Pract. 2022 Mar 19;2022:9338139. doi: 10.1155/2022/9338139. eCollection 2022.
As the completed studies have small sample sizes and different algorithms, a meta-analysis was conducted to assess the accuracy of WCE in identifying polyps using deep learning.
Two independent reviewers searched PubMed, Embase, the Web of Science, and the Cochrane Library for potentially eligible studies published up to December 8, 2021, which were analysed on a per-image basis. STATA RevMan and Meta-DiSc were used to conduct this meta-analysis. A random effects model was used, and a subgroup and regression analysis was performed to explore sources of heterogeneity.
Eight studies published between 2017 and 2021 included 819 patients, and 18,414 frames were eventually included in the meta-analysis. The summary estimates for the WCE in identifying polyps by deep learning were sensitivity 0.97 (95% confidence interval (CI), 0.95-0.98); specificity 0.97 (95% CI, 0.94-0.98); positive likelihood ratio 27.19 (95% CI, 15.32-50.42); negative likelihood ratio 0.03 (95% CI 0.02-0.05); diagnostic odds ratio 873.69 (95% CI, 387.34-1970.74); and the area under the sROC curve 0.99.
WCE uses deep learning to identify polyps with high accuracy, but multicentre prospective randomized controlled studies are needed in the future.
由于已完成的研究样本量较小且算法不同，因此进行了一项荟萃分析，以评估深度学习在识别息肉方面的 WCE 准确性。
两位独立审查员搜索了 PubMed、Embase、Web of Science 和 Cochrane Library，以查找截至 2021 年 12 月 8 日发表的潜在合格研究，这些研究基于图像进行分析。使用 STATA RevMan 和 Meta-DiSc 进行这项荟萃分析。使用随机效应模型，并进行亚组和回归分析以探索异质性的来源。
2017 年至 2021 年期间发表的八项研究纳入了 819 名患者，最终有 18414 个框架纳入荟萃分析。深度学习识别息肉的 WCE 的汇总估计值为：敏感性 0.97（95%置信区间（CI），0.95-0.98）；特异性 0.97（95% CI，0.94-0.98）；阳性似然比 27.19（95% CI，15.32-50.42）；阴性似然比 0.03（95% CI 0.02-0.05）；诊断比值比 873.69（95% CI，387.34-1970.74）；和 sROC 曲线下面积 0.99。
WCE 使用深度学习识别息肉的准确率高，但未来需要多中心前瞻性随机对照研究。
