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一种双频施加电位断层扫描技术:计算机模拟

A dual-frequency applied potential tomography technique: computer simulations.

作者信息

Griffiths H, Ahmed A

出版信息

Clin Phys Physiol Meas. 1987;8 Suppl A:103-7. doi: 10.1088/0143-0815/8/4a/014.

Abstract

Applied potential tomography has been discussed in relation to both static and dynamic imaging. We have investigated the feasibility of obtaining static images by measuring profiles at two frequencies of drive current to exploit the differing gradients of electrical conductivity with frequency for different tissues. This method has the advantages that no profile for the homogeneous medium is then needed, and the electrodes can be coupled directly to the skin. To demonstrate the principle, computer simulations have been carried out using published electrical parameters for mammalian tissues at frequencies of 100 and 150 kHz. The distribution of complex electric potentials was calculated by the successive over-relaxation method in two dimensions for an abdominal cross-section with 16 electrodes equally spaced around the surface. From the computed electrode potentials, images were reconstructed using a back-projection method (neglecting phase information). Liver and kidney appeared most distinctly on the image because of their comparatively large conductivity gradients. The perturbations in the electrode potential differences between the two frequencies had a mean value of 5%, requiring accurate measurement in a practical system, compared with 150% when the 100 kHz values were related to a simulation of homogeneous saline equal in conductivity to muscle. The perturbations could be increased by widening the separation of the frequencies. Static imaging using a dual-frequency technique appears to be feasible, but a more detailed consideration of the electrical properties of tissues is needed to determine the optimum choice of frequencies.

摘要

已针对静态和动态成像对应用电位断层扫描进行了讨论。我们研究了通过测量驱动电流两个频率下的剖面来获取静态图像的可行性,以利用不同组织电导率随频率的不同梯度。该方法的优点是不需要均匀介质的剖面,并且电极可直接与皮肤耦合。为了演示原理,已使用已发表的哺乳动物组织在100和150 kHz频率下的电参数进行了计算机模拟。通过逐次超松弛法在二维中计算了具有16个电极等间距分布在表面周围的腹部横截面的复电位分布。根据计算出的电极电位,使用反投影法(忽略相位信息)重建图像。肝脏和肾脏在图像上显得最为清晰,因为它们具有相对较大的电导率梯度。两个频率之间电极电位差的扰动平均值为5%,在实际系统中需要精确测量,而当100 kHz值与电导率与肌肉相等的均匀盐水模拟相关时,该扰动为150%。通过扩大频率间隔可增加扰动。使用双频技术的静态成像似乎是可行的,但需要更详细地考虑组织的电特性以确定频率的最佳选择。

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