Ouedraogo Pingdéwendé Victor, Traore Catherine, Savadogo Abdoul Aziz, Bagbila Wend Pagnangdé Abraham Hermann, Galboni Adama, Ouedraogo Abaz, Sere Ibrahima Stéphane, Millogo Athanase
Centre hospitalier universitaire Sourô Sanou, Bobo-Dioulasso, Burkina Faso.
Université Nazi Boni, Bobo-Dioulasso, Burkina Faso.
Med Trop Sante Int. 2022 Jan 17;2(1). doi: 10.48327/MTSI.2022.131. eCollection 2022 Mar 31.
Envenomation by snakebite is a public health problem in developing countries. Neurovascular complications are uncommon. We report two cases of hemorrhagic stroke at the Sourô Sanou Teaching Hospital in Bobo-Dioulasso, which complicate an envenomation.
The first patient was a 60-year-old woman with no history, who had been admitted 2 hours after snakebite for gingivorrhagia and consciousness disorders. Clinical examination found coma (GCS 7/15) and tetraparesis. The second patient was a 50-year-old woman with no history, who had been admitted one week after snakebite with digestive bleeding. Clinical examination found right hemiplegia and meningeal syndrome. Both patients presented hemorrhagic stroke on brain CT-scan but hemostasis assessment was normal. They received polyvalent antivenom and symptomatic treatment. The outcome was favorable for survival but with sequelae like tetraparesis for first patient and hemiparesis for second patient.
DISCUSSION - CONCLUSION: The hemorrhagic strokes are rare complications of snake envenomation. Venomous toxins can directly lead to the rupture of intracranial vessels apart of abnormalities of hemostasis. However, the morbidity and mortality related to envenomation by snake bite remains high in our environment.
在发展中国家,蛇咬伤中毒是一个公共卫生问题。神经血管并发症并不常见。我们报告了在博博迪乌拉索的苏罗·萨努教学医院发生的两例出血性中风病例,这是蛇咬伤中毒的并发症。
首例患者为一名60岁无病史女性,蛇咬伤后2小时因牙龈出血和意识障碍入院。临床检查发现昏迷(格拉斯哥昏迷量表评分为7/15)和四肢轻瘫。第二例患者为一名50岁无病史女性,蛇咬伤一周后因消化道出血入院。临床检查发现右侧偏瘫和脑膜刺激征。两名患者脑部CT扫描均显示出血性中风,但止血评估正常。他们接受了多价抗蛇毒血清和对症治疗。预后有利于存活,但首例患者有四肢轻瘫等后遗症,第二例患者有偏瘫后遗症。
讨论 - 结论:出血性中风是蛇咬伤中毒的罕见并发症。除止血异常外,毒液毒素可直接导致颅内血管破裂。然而,在我们所处的环境中,蛇咬伤中毒相关的发病率和死亡率仍然很高。