Ferreira Balan Vitor, Botticelli Daniele, Peñarrocha-Oltra David, Masuda Katsuhiko, Pires Godoy Eduardo, Xavier Samuel Porfirio
Chin J Dent Res. 2022 Jun 10;25(2):93-105. doi: 10.3290/j.cjdr.b3086337.
To compare the sequential healing of maxillary sinuses grafted with two different xenogeneic bone substitutes processed at either a low (300°C) or high (1200°C) temperature.
A sinus augmentation procedure was performed bilaterally in 20 rabbits and two different xenogeneic bone grafts were randomly used to fill the elevated spaces. Healing was studied after 2 and 10 weeks, in 10 rabbits during each period.
After 2 weeks of healing, very small amounts of new bone were observed in both groups, and were mainly confined to close to the sinus bone walls and osteotomy edges. After 10 weeks of healing, new bone was found in all regions, with higher percentages in those close to the bone walls and to the osteotomy. In this period of healing, the proportion of new bone in the 300°C group was 20.0% ± 4.3%, and in the 1200°C group it was 17.2% ± 4.3% (P = 0.162). In the 1200°C group, translucent, dark fog-like shadows in regions of the grafts were hiding portions of new bone (interpenetrating bone network).
Both biomaterials provided conditions that allowed bone growth within the elevated space, confirming that both biomaterials are suitable to be used as a graft for sinus floor augmentation.
比较用两种不同的异种骨替代物移植上颌窦的愈合情况,这两种替代物分别在低温(300°C)或高温(1200°C)下处理。
对20只兔子双侧进行鼻窦增高手术,随机使用两种不同的异种骨移植物填充抬高的间隙。在2周和10周后进行愈合研究,每个时间段各有10只兔子。
愈合2周后,两组均观察到少量新骨,主要局限于鼻窦骨壁和截骨边缘附近。愈合10周后,所有区域均发现新骨,靠近骨壁和截骨处的新骨百分比更高。在这个愈合阶段,300°C组的新骨比例为20.0%±4.3%,1200°C组为17.2%±4.3%(P = 0.162)。在1200°C组中,移植物区域的半透明、暗雾状阴影掩盖了部分新骨(相互贯穿的骨网络)。
两种生物材料都提供了使抬高间隙内骨生长的条件,证实这两种生物材料都适合用作鼻窦底增高的移植物。