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使用磁共振成像提高外周前庭障碍的诊断。

Using magnetic resonance imaging to improve diagnosis of peripheral vestibular disorders.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

J Neurol Sci. 2022 Aug 15;439:120300. doi: 10.1016/j.jns.2022.120300. Epub 2022 May 28.

Abstract

Peripheral vestibular disorders are caused by pathology of the inner ear. The majority of these disorders are diagnosed with a detailed history and vestibular physical exam. Imaging is rarely a part of diagnostic work up as the pathologies of these disorders are "invisible," or undetectable on imaging. However, these "invisible" diagnoses are becoming increasingly visible with advancements in imaging technology. Developments in magnetic resonance imaging are allowing for increased spatial resolution and better image contrast, improving our ability to see soft tissue structures including the membranous labyrinth, sensory epithelia and nerves. With these improvements in imaging, clinicians will be able to understand better atypical presentations of peripheral vestibular disorders, disease intractable to traditional therapy, disorders with unclear pathoetiology and disease only seen on histopathological studies. This review assesses the current state of imaging in the neurotology clinic with a special focus on magnetic resonance imaging and then gathers diseases identified by vestibular testing and histopathological studies that could be better understood with developments in imaging. In doing so, we hope to guide advancement in neurotologic imaging and apprise clinicians of the utility of imaging in peripheral vestibular disease diagnosis.

摘要

外周前庭障碍是由内耳病变引起的。这些疾病大多数通过详细的病史和前庭体格检查来诊断。由于这些疾病的病理是“不可见的”或在影像学上无法检测到,因此影像学很少作为诊断的一部分。然而,随着影像学技术的进步,这些“不可见的”诊断变得越来越可见。磁共振成像的发展使空间分辨率提高,图像对比度更好,从而提高了我们观察包括膜迷路、感觉上皮和神经在内的软组织结构的能力。随着影像学的这些改进,临床医生将能够更好地理解外周前庭障碍的非典型表现、对传统治疗方法耐药的疾病、病因不明的疾病以及仅在组织病理学研究中可见的疾病。这篇综述评估了影像学在神经耳科学诊所中的现状,特别关注磁共振成像,然后收集了通过前庭测试和组织病理学研究确定的疾病,如果影像学有新的发展,这些疾病将可以得到更好的理解。通过这样做,我们希望能指导神经耳科影像学的进步,并让临床医生了解影像学在外周前庭疾病诊断中的应用。

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