抑制角质形成细胞衍生的信号转导和转录激活因子6可改善小鼠特应性皮炎。 - Suppr | 超能文献

Inhibiting Keratinocyte-Derived Signal Transducer and Activator of Transcription 6 Improved Atopic Dermatitis in Mice.

作者信息

Xue Shanghai, Zhu Renkai, Chen Weiwei, Yang Hua, Wang Jiafu, Meng Jianghui

机构信息

School of Life Sciences, Henan University, Kaifeng, China.

School of Biotechnology, Faculty of Science and Health, Dublin City University, Dublin, Ireland.

出版信息

J Invest Dermatol. 2022 Dec;142(12):3341-3345.e14. doi: 10.1016/j.jid.2022.05.1087. Epub 2022 Jun 9.

DOI:10.1016/j.jid.2022.05.1087

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Inhibiting Keratinocyte-Derived Signal Transducer and Activator of Transcription 6 Improved Atopic Dermatitis in Mice.抑制角质形成细胞衍生的信号转导和转录激活因子6可改善小鼠特应性皮炎。

J Invest Dermatol. 2022 Dec;142(12):3341-3345.e14. doi: 10.1016/j.jid.2022.05.1087. Epub 2022 Jun 9.

2

Interleukin-4 up-regulation of epidermal interleukin-19 expression in keratinocytes involves the binding of signal transducer and activator of transcription 6 (Stat6) to the imperfect Stat6 sites.白细胞介素-4上调角质形成细胞中表皮白细胞介素-19的表达涉及信号转导和转录激活因子6（Stat6）与不完全Stat6位点的结合。

Immunology. 2014 Dec;143(4):601-8. doi: 10.1111/imm.12339.

3

The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling.JAK 抑制剂 JTE-052 通过抑制信号转导子和转录激活子 3 信号通路改善皮肤屏障功能。

J Allergy Clin Immunol. 2015 Sep;136(3):667-677.e7. doi: 10.1016/j.jaci.2015.03.051. Epub 2015 Jun 24.

4

Crocin Ameliorates Atopic Dermatitis Symptoms by down Regulation of Th2 Response via Blocking of NF-κB/STAT6 Signaling Pathways in Mice.藏红花苷通过抑制 NF-κB/STAT6 信号通路减轻小鼠特应性皮炎症状。

Nutrients. 2018 Nov 2;10(11):1625. doi: 10.3390/nu10111625.

5

IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1, 2/Stat6 signal transduction pathway: Implication for atopic dermatitis.IL-4 通过 Jak1、2/Stat6 信号转导通路调节角质形成细胞中的趋化因子 CCL26：对特应性皮炎的影响。

Mol Immunol. 2012 Feb;50(1-2):91-7. doi: 10.1016/j.molimm.2011.12.008. Epub 2012 Jan 5.

6

Piperine Ameliorates Trimellitic Anhydride-Induced Atopic Dermatitis-Like Symptoms by Suppressing Th2-Mediated Immune Responses via Inhibition of STAT6 Phosphorylation.胡椒碱通过抑制 STAT6 磷酸化抑制 Th2 介导的免疫应答来改善三油酸酐诱导的特应性皮炎样症状。

Molecules. 2020 May 7;25(9):2186. doi: 10.3390/molecules25092186.

7

Interleukin-4 Downregulation of Involucrin Expression in Human Epidermal Keratinocytes Involves Stat6 Sequestration of the Coactivator CREB-Binding Protein.白细胞介素-4下调人表皮角质形成细胞中兜甲蛋白的表达涉及信号转导和转录激活因子6对共激活因子CREB结合蛋白的隔离。

J Interferon Cytokine Res. 2016 Jun;36(6):374-81. doi: 10.1089/jir.2015.0056. Epub 2016 Feb 26.

8

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.信号转导子和转录激活子 6 基因（STAT6）增加了特应性皮炎患者发生播散性病毒性皮肤感染的倾向。

J Allergy Clin Immunol. 2011 Nov;128(5):1006-14. doi: 10.1016/j.jaci.2011.06.003. Epub 2011 Jul 18.

9

Poly-ADP ribose polymerase-14 limits severity of allergic skin disease.聚-ADP核糖聚合酶-14限制过敏性皮肤病的严重程度。

Immunology. 2017 Nov;152(3):451-461. doi: 10.1111/imm.12782. Epub 2017 Jul 27.

10

Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6.兜甲蛋白和内披蛋白的表达通过信号转导子和转录激活子6（STAT-6）被辅助性T细胞2（Th2）细胞因子下调。

Clin Immunol. 2008 Mar;126(3):332-7. doi: 10.1016/j.clim.2007.11.006. Epub 2007 Dec 31.

引用本文的文献

1

Critical Players and Therapeutic Targets in Chronic Itch.慢性瘙痒的关键参与者和治疗靶点。

Int J Mol Sci. 2022 Sep 1;23(17):9935. doi: 10.3390/ijms23179935.