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预测美国补偿活体肾脏捐献者的经济影响:成本效益分析显示患者和社会将获得巨大收益。

Projecting the Economic Impact of Compensating Living Kidney Donors in the United States: Cost-Benefit Analysis Demonstrates Substantial Patient and Societal Gains.

机构信息

U.S. Economic and Financial Research, Bank of America (Retired), Walnut Creek, CA, USA.

Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA.

出版信息

Value Health. 2022 Dec;25(12):2028-2033. doi: 10.1016/j.jval.2022.04.1732. Epub 2022 Jun 9.

DOI:10.1016/j.jval.2022.04.1732
PMID:35690519
Abstract

OBJECTIVES

The aim of this study was to show how the US government could save approximately 47 000 patients with chronic kidney failure each year from suffering on dialysis and premature death by compensating living kidney donors enough to completely end the kidney shortage.

METHODS

Supply and demand analysis was used to estimate the number of donated kidneys needed to end the kidney shortage and the level of compensation required to encourage this number of donations. These results were then input into a detailed cost-benefit analysis to estimate the economic value of kidney transplantation to (1) the average kidney recipient and their caregiver, (2) taxpayers, and (3) society in general.

RESULTS

We estimate half of patients diagnosed with kidney failure each year-approximately 62 000 patients-could be saved from suffering on dialysis and premature death if they could receive an average of 1½ kidney transplants. However, currently there are only enough donated kidneys to save approximately 15 000 patients. To encourage sufficient donations to save the other 47 000 patients, the government would have to compensate living kidney donors approximately $77 000 (±50%) per donor. The value of transplantation to an average kidney recipient (and caregiver) would be approximately $1.5 million, and the savings from the recipient not needing expensive dialysis treatments would be approximately $1.2 million.

CONCLUSIONS

This analysis reveals the huge benefit that compensating living kidney donors would provide to patients with kidney failure and their caregivers and, conversely, the huge cost that is being imposed on these patients and their families by the current legal prohibition against such compensation.

摘要

目的

本研究旨在展示美国政府如何通过向活体肾脏捐献者提供足够的补偿,使每年约 4.7 万名慢性肾衰竭患者免于接受透析和过早死亡,从而彻底解决肾脏短缺问题。

方法

采用供需分析来估算结束肾脏短缺所需的捐献肾脏数量,以及鼓励这一数量的捐赠所需的补偿水平。然后,将这些结果输入到详细的成本效益分析中,以估算肾脏移植对(1)普通肾脏接受者及其护理人员、(2)纳税人和(3)整个社会的经济价值。

结果

我们估计,如果每年诊断出的一半肾衰竭患者(约 6.2 万名患者)能够平均接受 1 个半肾脏移植,他们中的一半人可以避免接受透析和过早死亡。然而,目前只有足够的捐献肾脏可以拯救大约 1.5 万名患者。为了鼓励足够的捐赠来拯救其余 4.7 万名患者,政府必须向活体肾脏捐献者提供约 7.7 万美元(±50%)的补偿。对普通肾脏接受者(及其护理人员)来说,移植的价值约为 150 万美元,而接受者无需接受昂贵的透析治疗所节省的费用约为 120 万美元。

结论

本分析揭示了补偿活体肾脏捐献者将为肾衰竭患者及其护理人员带来的巨大好处,而当前法律禁止这种补偿则给这些患者及其家庭带来了巨大的成本。

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Projecting the Economic Impact of Compensating Living Kidney Donors in the United States: Cost-Benefit Analysis Demonstrates Substantial Patient and Societal Gains.预测美国补偿活体肾脏捐献者的经济影响:成本效益分析显示患者和社会将获得巨大收益。
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Clin J Am Soc Nephrol. 2025 Mar 1;20(3):458-461. doi: 10.2215/CJN.0000000633. Epub 2024 Nov 22.
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A fair exchange: why living kidney donors in England should be financially compensated.公平交换:为何英国活体肾脏捐献者应该得到经济补偿
Med Health Care Philos. 2023 Dec;26(4):625-634. doi: 10.1007/s11019-023-10171-x. Epub 2023 Aug 24.