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[感染所致精神障碍。在抗生素时代它们仍然是热门话题吗?]

[Infection-caused mental disorders. Are they still topical in the antibiotic era?].

作者信息

Marneros A, Rohde A, Otto K M

出版信息

Dtsch Med Wochenschr. 1987 May 15;112(20):796-800. doi: 10.1055/s-2008-1068142.

Abstract

Of 104 patients treated in a psychiatric hospital because of mental disturbances caused by an infection, almost one-half had been referred directly to the psychiatric hospital on account of their psychically abnormal behaviour. The infectious disease causing these disturbances was diagnosed only after their admission. In most of the cases the psychic abnormalities did not seem to be due to a physical cause, so that the somatic examination was frequently delayed. Pneumonic infections were most frequently seen, but there were also numerous other infections from all other disciplines of medicine. Clouding of consciousness developed rapidly in 84% of the patients during the course of inpatient treatment with an incidence that was almost fivefold that of the initial stage. Visual hallucinations (37%) were the most frequent productive-psychotic phenomenon. 45% of the patients presented with a delirious pattern and 4% with a psychosis resembling schizophrenia. In 35% of the patients treatment with psychotropic drugs proved necessary, whereas with the remaining 65% therapy remained antibiotic or generally somatic only. 18% of the patients died.

摘要

在一家精神病院接受治疗的104名因感染导致精神障碍的患者中,近一半因精神行为异常而被直接转诊至该精神病院。导致这些障碍的传染病在他们入院后才被诊断出来。在大多数病例中,精神异常似乎并非由身体原因引起,因此体格检查常常被推迟。肺炎感染最为常见,但也有来自医学其他所有学科的大量其他感染。在住院治疗过程中,84%的患者意识迅速模糊,其发生率几乎是初始阶段的五倍。视幻觉(37%)是最常见的幻觉性精神病现象。45%的患者表现为谵妄模式,4%的患者表现为类似精神分裂症的精神病。35%的患者被证明有必要使用精神药物治疗,而其余65%的患者仅接受抗生素或一般躯体治疗。18%的患者死亡。

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