Huang Xun, Wang Lin, Chen Yangjing, Liu Jianlin, Liu Yamin, Yang Lin
Department of Vascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Department of Critical Care Medicine, Xi'an Traditional Chinese Medicine Hospital, Xi'an, China.
Front Oncol. 2022 May 25;12:860788. doi: 10.3389/fonc.2022.860788. eCollection 2022.
Till now, the effect of different embolic materials (particulate vs coil) on pre-embolization of carotid body tumors remains poorly understood. The aim of this study was to explore the comparative results between particulate and coil embolization for carotid body tumors. Thirty-seven patients with carotid body tumors who underwent embolization before surgical resection were reviewed and analyzed in this retrospective study between 2008 and 2020. Twenty-one patients were included in the particulate group, while 16 patients were included in the coil group. All procedure-related details, complications and 5-year follow-up data were collected in the study. The preoperative embolization time was obviously longer in the particulate group than in the coil group (42.6 ± 12.3 min vs. 33.7 ± 10.1 min, =.02), and the fluo time of the procedure (864.5 ± 240.9 s vs. 729.6 ± 251.5 s) and cumulative air kerma (634.6 ± 188.4 mGy vs. 486.7 ± 164.7 mGy) value were higher in the particulate group ( =.01). The incidences of total adverse events in both groups were not significantly different (28.6% vs. 25.0%, >.05); however, two cases of ectopic embolization only occurred in the particulate group. Interestingly, medical expenditure was higher in the particulate group than in the coil group ( =.02). For the 3-year follow-up evaluation, recurrence and all-cause mortality were similar in both groups ( >.05). Preoperative embolization with coils could be relatively safe, have a lower radiation dosage and be cost-effective for the treatment of carotid body tumors.
迄今为止，不同栓塞材料（颗粒与弹簧圈）对颈动脉体瘤栓塞前的影响仍知之甚少。本研究的目的是探讨颗粒栓塞与弹簧圈栓塞治疗颈动脉体瘤的对比结果。在这项回顾性研究中，对2008年至2020年间37例在手术切除前接受栓塞治疗的颈动脉体瘤患者进行了回顾和分析。颗粒组纳入21例患者，弹簧圈组纳入16例患者。研究收集了所有与手术相关的细节、并发症及5年随访数据。颗粒组的术前栓塞时间明显长于弹簧圈组（42.6±12.3分钟对33.7±10.1分钟， =0.02），颗粒组的手术透视时间（864.5±240.9秒对729.6±251.5秒）和累积空气比释动能（634.6±188.4毫戈瑞对486.7±164.7毫戈瑞）值更高（ =0.01）。两组总不良事件的发生率无显著差异（28.6%对25.0%， >0.05）；然而，仅颗粒组发生了2例异位栓塞。有趣的是，颗粒组的医疗费用高于弹簧圈组（ =0.02）。在3年随访评估中，两组的复发率和全因死亡率相似（ >0.05）。术前用弹簧圈进行栓塞治疗颈动脉体瘤可能相对安全，辐射剂量较低且具有成本效益。
