The First Department of General Surgery, Suzhou First People's Hospital, Anhui Province, Suzhou, Anhui 234000, China.
Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, Anhui 230000, China.
Comput Math Methods Med. 2022 Jun 3;2022:9110676. doi: 10.1155/2022/9110676. eCollection 2022.
Evaluate the influence of laparoscopy combined with choledochoscopy on operation-related indexes, serum total bilirubin (TBIL) level, and abdominal drainage tube extraction time within cases carrying cholecystolithiasis/choledocholithiasis.
86 cases of cholecystolithiasis together with choledocholithiasis were chosen for this investigation, and cases were randomly segregated within the control cohort (43 cases, open surgery) and observation cohort (43 cases, laparoscopy combined with choledochoscopy).The operation-related indexes, complete stone clearance rate, postoperative visual analogue scale (VAS) scoring, serum TBIL level, and postsurgical complications/recovery incidence were observed and comparatively analyzed across cohorts.
Compared with the control cohort, the incision length, operation duration, postoperative exhaust duration, abdominal drainage tube extraction time, and postsurgery hospitalization in observation cohort were markedly reduced ( < 0.05), the intrasurgical hemorrhaging was markedly reduced ( < 0.05), and the postoperative complication incidences were markedly reduced ( < 0.05). Furthermore, the complete stone clearance rates in the observation cohort were elevated compared with control, but the difference was not statistically significant ( > 0.05).VAS scoring for the observation cohort at 6, 12, 24, and 48 hours postsurgery was markedly reduced ( < 0.05). On the first day after the operation, the serum TBIL levels for the two cohorts were very high and gradually decreased, and the serum TBIL levels in the observation cohort were markedly reduced during day 1, 3, and 5 postsurgery ( < 0.05).
Laparoscopy combined with choledochoscopy surgical treatment might reduce the surgery duration, intrasurgery hemorrhaging, postsurgical pain, and liver function damage.
评估腹腔镜联合胆道镜治疗胆囊结石合并胆总管结石的手术相关指标、血清总胆红素（TBIL）水平及腹腔引流管拔除时间的影响。
选择 86 例胆囊结石合并胆总管结石患者，对照组（43 例，行开腹手术）和观察组（43 例，行腹腔镜联合胆道镜手术）。观察两组手术相关指标、结石清除率、术后视觉模拟评分（VAS）、血清 TBIL 水平及术后并发症/恢复情况。
观察组切口长度、手术时间、术后排气时间、腹腔引流管拔除时间及术后住院时间均明显短于对照组（ < 0.05），术中出血量明显减少（ < 0.05），术后并发症发生率明显降低（ < 0.05）。观察组结石清除率高于对照组，但差异无统计学意义（ > 0.05）。观察组术后 6、12、24、48 小时 VAS 评分明显降低（ < 0.05）。术后第 1 天两组血清 TBIL 水平均较高，逐渐下降，观察组术后第 1、3、5 天血清 TBIL 水平明显降低（ < 0.05）。
腹腔镜联合胆道镜治疗可缩短手术时间、减少术中出血、减轻术后疼痛、减轻肝功能损害。
