用¹³³氙对犬左心室功能和局部心肌灌注进行测量。
Measurement of both left ventricular function and regional myocardial perfusion with 133Xe in dogs.
作者信息
Ruddy T D, Yasuda T, Barlai-Kovach M, Nedelman M A, Moore R H, Alpert N M, Correia J A, Newell J B, Okada R D, Boucher C A
出版信息
Eur J Nucl Med. 1987;12(11):533-41. doi: 10.1007/BF00296092.
A technique to measure left ventricular (LV) function and myocardial perfusion was validated in 12 dogs. 133Xe in saline was injected into the left atrium (LA) or LV and two data sets were obtained using gamma camera imaging: 1) A first pass gated scan for LV function; followed by 2) Sequential images for regional myocardial perfusion. LV ejection fraction and wall motion measurements from the 133Xe blood pool images were compared to ejection fraction (r = 0.88, P less than 0.01) and wall motion (r = 0.83, P less than 0.01) data from 99mTc labeled blood pool scans. The perfusion measurements obtained with the 133Xe method were compared to microsphere data (r = 0.79, P less than 0.01). Measurements after LV 133Xe injection were similar to data following LA injection. Thus, quantitative assessment of global LV function, regional wall motion and myocardial perfusion is possible with LA or LV 133Xe injection and gamma camera imaging.
一种测量左心室（LV）功能和心肌灌注的技术在12只狗身上得到验证。将盐水中的133Xe注入左心房（LA）或左心室，使用γ相机成像获得两组数据：1）用于左心室功能的首次通过门控扫描；接着是2）用于区域心肌灌注的序列图像。将133Xe血池图像中的左心室射血分数和壁运动测量值与99mTc标记血池扫描中的射血分数（r = 0.88，P小于0.01）和壁运动（r = 0.83，P小于0.01）数据进行比较。将133Xe方法获得的灌注测量值与微球数据进行比较（r = 0.79，P小于0.01）。左心室注射133Xe后的测量结果与左心房注射后的数据相似。因此，通过左心房或左心室注射133Xe并进行γ相机成像，可以对整体左心室功能、区域壁运动和心肌灌注进行定量评估。
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