Bobis Villagrá Diego, Almeida Mariana, Cox Alistair, Henderson Elisabeth
Lumbry Park Veterinary Specialists, Alton, UK.
FINN Pathologists, Norfolk, UK.
JFMS Open Rep. 2022 Jun 7;8(1):20551169221098328. doi: 10.1177/20551169221098328. eCollection 2022 Jan-Jun.
A 7-year-old female neutered domestic shorthair cat was presented with weight loss, abdominal distension, lethargy, pyrexia and hyporexia. Haematology and biochemistry were unremarkable. Abdominal ultrasound revealed a cystic mass within the left cranial abdominal quadrant, adjacent to the pancreas, stomach and spleen. CT revealed a 10.5 cm, rounded, well-encapsulated, hypodense mass arising from the left pancreatic lobe. The remaining organs of the abdominal and thoracic cavity were unremarkable. A partial left lobe pancreatectomy and splenic lymph node removal were performed. Histopathology of the pancreatic mass reported a proliferating population of neoplastic spindle cells most consistent with a preliminary diagnosis of soft tissue sarcoma. Immunohistochemistry characteristics, together with the morphological findings, were consistent with a diagnosis of leiomyosarcoma. The patient recovered without any concerns after receiving routine postoperative care. Clinical examination and abdominal ultrasound 5 months postoperatively revealed no abnormalities.
To our knowledge, this is the first report of pancreatic leiomyosarcoma in a cat. Pancreatic leiomyosarcoma should be considered as one of the possible differential diagnoses for cats presenting with a pancreatic mass.
一只7岁已绝育的雌性家养短毛猫出现体重减轻、腹部膨胀、嗜睡、发热和食欲减退症状。血液学和生物化学检查无异常。腹部超声显示左腹上象限有一个囊性肿块，毗邻胰腺、胃和脾脏。CT显示一个10.5厘米的圆形、边界清晰、低密度肿块，起源于左胰叶。腹腔和胸腔的其余器官未见异常。进行了左叶部分胰腺切除术和脾淋巴结切除术。胰腺肿块的组织病理学报告显示有一群增生的肿瘤性梭形细胞，初步诊断最符合软组织肉瘤。免疫组织化学特征与形态学结果一致，诊断为平滑肌肉瘤。患者在接受常规术后护理后康复，无任何问题。术后5个月的临床检查和腹部超声显示无异常。
据我们所知，这是猫胰腺平滑肌肉瘤的首例报告。胰腺平滑肌肉瘤应被视为出现胰腺肿块的猫可能的鉴别诊断之一。
