Soo Wai Tseung, Teo Eu Gene, Mohamad Noraini, Wong Albert Sii Hieng
Department of Surgery, Sarawak General Hospital, Ministry of Health, Sarawak, Malaysia.
Department of Surgery, University Malaya Medical Center, Ministry of Higher Education, Kuala Lumpur, Malaysia.
J Neurosci Rural Pract. 2022 Mar 3;13(2):351-353. doi: 10.1055/s-0042-1743446. eCollection 2022 Apr.
Uterine Leiomyosarcoma (uLMS) is an aggressive tumor with poor clinical outcome. Skull and dural metastasis from uterine uLMS is exceptionally rare. We report a 60-year-old woman who had a 6 months' history of per vaginal bleed and abdominal pain who presented to us in a confused state and raised intracranial pressure symptoms with swelling over her right frontal-temporal region. She underwent excision of the right frontal-temporal tumor and evacuation of a right subdural hematoma (SDH), which greatly improved her condition. Postoperatively, she underwent adjuvant radiotherapy and chemotherapy. This case highlights the importance of clinical suspicion to diagnose patients with this rare metastasis to this region and the appropriate subsequent treatment. We herein report a rare case of metastatic uLMS with skull and dural metastasis that presented with SDH.
子宫平滑肌肉瘤（uLMS）是一种侵袭性肿瘤，临床预后较差。子宫uLMS发生颅骨和硬脑膜转移极为罕见。我们报告一名60岁女性，有6个月的经阴道出血和腹痛病史，前来就诊时处于意识模糊状态，伴有颅内压升高症状，右侧额颞部肿胀。她接受了右侧额颞部肿瘤切除术及右侧硬膜下血肿（SDH）清除术，病情大为改善。术后，她接受了辅助放疗和化疗。该病例凸显了临床怀疑对于诊断该区域罕见转移患者的重要性以及后续适当治疗的重要性。我们在此报告一例罕见的伴有颅骨和硬脑膜转移并表现为SDH的转移性uLMS病例。
