利用单克隆抗体HAE9鉴定一种人类红细胞表面抗原。
Identification of a human erythroid cell surface antigen by monoclonal antibody HAE9.
作者信息
Mechetner E B, Tonevitsky A G, Ievleva E S, Rozinova E N, Popova O N
出版信息
Exp Hematol. 1987 May;15(4):355-9.
PMID:3569438
Abstract
A noncytotoxic monoclonal antibody (IgM) HAE9 that selectively binds to 36% CFU-E and more than 90% nucleated erythroid cells in human bone marrow is described. This antibody recognizes a 70-kDa-membrane protein. It is suggested that HAE9 is directed to a human epitope of Ag-Eb, an interspecies mammalian erythroid-specific cell surface marker.
摘要
描述了一种非细胞毒性单克隆抗体（IgM）HAE9，它能选择性地结合人骨髓中36%的红细胞集落形成单位（CFU-E）和90%以上的有核红细胞。该抗体识别一种70 kDa的膜蛋白。有人提出，HAE9针对的是Ag-Eb的人类表位，Ag-Eb是一种种间哺乳动物红细胞特异性细胞表面标志物。
Zotero 插件