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清醒、未用药、脊髓横断猫的皮肤脊髓背角神经元自发活动缺失

Lack of spontaneous activity of cutaneous spinal dorsal horn neurons in awake, drug-free, spinally transected cats.

作者信息

Collins J G, Ren K, Tang J

出版信息

Exp Neurol. 1987 May;96(2):299-306. doi: 10.1016/0014-4886(87)90048-3.

DOI:10.1016/0014-4886(87)90048-3
PMID:3569456
Abstract

Extracellular single-unit activity was recorded from neurons with cutaneous input in the dorsal horn of the spinal cord (L4-L6) of awake, drug-free cats before (for several weeks) and after (day 1 through day 7) cord transection (T12). The spontaneous activity of the neurons was minimal or nonexistent in both recording conditions. The lack of spontaneous activity following spinal cord transection contrasts sharply with activity recorded in acute spinal-cord transected preparations in which high rates of spontaneous activity have been reported. This discrepancy may reflect an important difference between the chronic, awake, drug-free and acute preparations.

摘要

在清醒、未用药的猫的脊髓背角(L4-L6)中,记录了具有皮肤输入的神经元的细胞外单单位活动,记录时间为脊髓横断(T12)前(持续数周)和横断后第1天至第7天。在两种记录条件下,神经元的自发活动都极少或不存在。脊髓横断后自发活动的缺乏与急性脊髓横断标本中记录到的活动形成鲜明对比,在急性脊髓横断标本中已报道有高自发活动率。这种差异可能反映了慢性、清醒、未用药标本与急性标本之间的重要区别。

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Lack of spontaneous activity of cutaneous spinal dorsal horn neurons in awake, drug-free, spinally transected cats.清醒、未用药、脊髓横断猫的皮肤脊髓背角神经元自发活动缺失
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