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[钾和水在冷适应大鼠棕色脂肪组织中的沉积]

[Deposition of potassium and water in the brown adipose tissue of cold-adapted rats].

作者信息

Medvedev L N, Zamaĭ T N, Medvedeva S E

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1987 Jan;73(1):124-9.

PMID:3569574
Abstract

The rats adapted to 0-4 degrees C increased water content in the BAT. The Na and K intracellular contents was unaltered during first month of the adaptation. K content in the BAT was considerably increased by the 10th and 18th weeks of the adaptation. A positive correlation between Na and K contents was revealed in the BAT of both adapted and unadapted rats. The increase of K concentration and the decrease of Na/K ratio suggest that, in prolonged adaptation, the Na-pump power grows more than is necessary for compensation of the high fluxes of cations through the cell membranes in the BAT.

摘要

适应0至4摄氏度环境的大鼠棕色脂肪组织(BAT)中的含水量增加。在适应的第一个月,细胞内钠和钾的含量未发生改变。在适应的第10周和第18周,BAT中的钾含量显著增加。在适应和未适应的大鼠的BAT中,钠和钾含量之间均呈现正相关。钾浓度的增加以及钠/钾比值的降低表明,在长期适应过程中,钠泵的功能增强幅度超过了补偿BAT细胞膜中阳离子高通量所需的水平。

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