Suppr超能文献

产前风险评分预测肩难产,重点关注胎儿超声数据。

Antenatal risk score for prediction of shoulder dystocia with focus on fetal ultrasound data.

机构信息

Berlin Center for Diabetes and Pregnancy, Department for Obstetrics and Gynecology, St. Joseph Hospital, Berlin, Germany.

Department for Obstetrics, Campus Virchow, Charité, Humboldt University, Berlin, Germany.

出版信息

Am J Obstet Gynecol. 2022 Nov;227(5):753.e1-753.e8. doi: 10.1016/j.ajog.2022.06.008. Epub 2022 Jun 11.

Abstract

BACKGROUND

Shoulder dystocia is one of the most threatening complications during delivery, and although it is difficult to predict, individual risk should be considered when counseling for mode of delivery.

OBJECTIVE

This study aimed to develop and validate a risk score for shoulder dystocia based on fetal ultrasound and maternal data from 15,000 deliveries.

STUDY DESIGN

Data were retrospectively obtained of deliveries in 3 tertiary centers between 2014 and 2017 for the derivation cohort and between 2018 and 2020 for the validation cohort. Inclusion criteria were singleton pregnancy, vaginal delivery in cephalic presentation at ≥37+0 weeks' gestation, and fetal biometry data available within 2 weeks of delivery. Independent predictors were determined by multivariate regression analysis in the derivation cohort, and a score was developed on the basis of the effect of the predictors.

RESULTS

The derivation cohort consisted of 7396 deliveries with a 0.91% rate of shoulder dystocia, and the validation cohort of 7965 deliveries with a 1.0% rate of shoulder dystocia. Among all women, 13.8% had diabetes mellitus, and 12.1% were obese (body mass index ≥30 kg/m). Independent risk factors in the derivation cohort were: estimated fetal weight ≥4250 g (odds ratio, 4.27; P=.002), abdominal-head-circumference ≥2.5 cm (odds ratio, 3.96; P<.001), and diabetes mellitus (odds ratio, 2.18; P=.009). On the basis of the strength of effect, a risk score was developed: estimated fetal weight ≥4250 g=2, abdominal-head-circumference ≥2.5 cm=2, and diabetes mellitus=1. The risk score predicted shoulder dystocia with moderate discriminatory ability (area under the receiver-operating characteristic curve, 0.69; P<.001; area under the receiver-operating characteristic curve, 0.71; P<.001) and good calibration (Hosmer-Lemeshow goodness-of-fit; P=.466; P=.167) for the derivation and validation cohorts, respectively. With 1 score point, 16 shoulder dystocia cases occurred in 1764 deliveries, with 0.6% shoulder dystocia incidence and a number needed to treat with cesarean delivery to avoid 1 case of shoulder dystocia of 172 (2 points: 38/1809, 2.1%, 48; 3 points: 18/336, 5.4%, 19; 4 points: 10/96, 10.5%, 10; and 5 points: 5/20, 25%, 4); 40.8% of the shoulder dystocia cases occurred without risk factors.

CONCLUSION

The presented risk score for shoulder dystocia may act as a supplemental tool for the clinical decision-making regarding mode of delivery. According to our score model, in pregnancies with a score ≤2, meaning having solely estimated fetal weight ≥4250 g, or abdominal-head-circumference ≥2.5, or diabetes mellitus, cesarean delivery for prevention of shoulder dystocia should not be recommended because of the high number needed to treat to avoid 1 case of shoulder dystocia. Conversely, in patients with a score of ≥4 with or without diabetes mellitus, cesarean delivery may be considered. However, in 40% of the shoulder dystocia cases, no risk factors had been present.

摘要

背景

肩难产是分娩过程中最具威胁性的并发症之一,尽管难以预测,但在选择分娩方式时应考虑个体风险。

目的

本研究旨在基于 15000 例分娩的胎儿超声和产妇数据,开发和验证一种肩难产风险评分。

研究设计

回顾性获取了 2014 年至 2017 年期间 3 家三级中心的分娩数据作为推导队列,以及 2018 年至 2020 年期间的验证队列。纳入标准为单胎妊娠、头位阴道分娩、妊娠≥37+0 周、分娩前 2 周内有胎儿生物测量数据。在推导队列中,通过多变量回归分析确定独立预测因素,并基于预测因素的影响制定评分。

结果

推导队列包括 7396 例分娩,肩难产发生率为 0.91%,验证队列包括 7965 例分娩,肩难产发生率为 1.0%。所有女性中,13.8%患有糖尿病,12.1%肥胖(体重指数≥30kg/m²)。推导队列中的独立危险因素为:估计胎儿体重≥4250g(优势比,4.27;P=.002)、腹围-头围≥2.5cm(优势比,3.96;P<.001)和糖尿病(优势比,2.18;P=.009)。基于效应强度,制定了一个风险评分:估计胎儿体重≥4250g=2,腹围-头围≥2.5cm=2,糖尿病=1。该风险评分具有中等的预测肩难产的能力(接受者操作特征曲线下面积,0.69;P<.001;验证队列,0.71;P<.001),且校准良好(Hosmer-Lemeshow 拟合优度检验;P=.466;P=.167),分别适用于推导和验证队列。风险评分每增加 1 分,在 1764 例分娩中发生 16 例肩难产,肩难产发生率为 0.6%,为避免 1 例肩难产需要行剖宫产的治疗人数为 172(1 分:38/1809,2.1%,48;2 分:38/1809,2.1%,48;3 分:18/336,5.4%,19;4 分:10/96,10.5%,10;5 分:5/20,25%,4);40.8%的肩难产病例无危险因素。

结论

本研究提出的肩难产风险评分可作为临床决策有关分娩方式的辅助工具。根据我们的评分模型,在评分≤2 的妊娠中,即仅存在估计胎儿体重≥4250g、腹围-头围≥2.5cm 或糖尿病,为预防肩难产,不建议行剖宫产,因为需要行剖宫产治疗的人数较多才能避免 1 例肩难产。相反,对于评分≥4 且有或无糖尿病的患者,可考虑行剖宫产。然而,在 40%的肩难产病例中,并无危险因素存在。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验