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如何在晚期卵巢癌患者中在不打开胸腔的情况下对浸润膈肌的腹膜癌结节进行完全切除。

How to perform complete resection of peritoneal carcinomatosis nodules infiltrating the diaphragm without opening the pleural cavity in patients with advanced-stage ovarian cancers.

机构信息

Department of Gynecology and Obstetrics, Valais Hospital, Av. du Grand-Champsec 80, 1951 Sion, Switzerland; Department of Pediatrics, Gynecology and Obstetrics, Geneva University Hospitals, Boulevard de la Cluse 30, 1205 Geneva, Switzerland.

Department of thoracic surgery, Valais Hospital, Av. du Grand-Champsec 80, 1951 Sion, Switzerland.

出版信息

J Gynecol Obstet Hum Reprod. 2022 Sep;51(7):102430. doi: 10.1016/j.jogoh.2022.102430. Epub 2022 Jun 10.

DOI:10.1016/j.jogoh.2022.102430
PMID:35697249
Abstract

Patients with advanced-stage ovarian cancer frequently present with peritoneal carcinomatosis, and a diaphragmatic involvement is observed in about 40% of cases. The goal of treatment includes complete surgical cytoreduction associated with systemic chemotherapy. Complete diaphragmatic cytoreduction is a crucial step and plays a major role in the overall survival of these patients. Deep infiltrating peritoneal carcinomatosis nodules are treated with diaphragmatic full-thickness resections, but these procedures involve opening the pleural cavity and are associated with a high rate of postoperative complications, such as pleural effusion and pneumothorax. A chest drain is often required, causing significant discomfort for the patients and potentially being an additional source of complications. In this study, we present a novel surgical technique to perform diaphragmatic resections using a linear stapler without opening the pleural cavity or needing a chest drain.

摘要

晚期卵巢癌患者常出现腹膜癌病,约 40%的病例存在膈肌受累。治疗目标包括与全身化疗相关的完全手术细胞减灭术。完全的膈肌细胞减灭术是一个关键步骤,对这些患者的总生存起着重要作用。深部浸润性腹膜癌病结节用膈肌全层切除术治疗,但这些手术需要打开胸腔,并且与术后并发症(如胸腔积液和气胸)的高发生率相关。通常需要放置胸腔引流管,这会给患者带来明显的不适,并可能成为并发症的另一个来源。在本研究中,我们提出了一种新的手术技术,使用线性吻合器进行膈肌切除术,无需打开胸腔或放置胸腔引流管。

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