Thatcher B S, Sivak M V, Tedesco F J, Vennes J A, Hutton S W, Achkar E A
Gastrointest Endosc. 1987 Apr;33(2):91-5. doi: 10.1016/s0016-5107(87)71517-x.
Fifty-one patients who underwent endoscopic sphincterotomy for suspected dysfunction of the sphincter of Oddi were evaluated retrospectively. The procedure resulted in complete abolition of pain allowing discontinuation of analgesics in 31 of the 46 patients available for follow-up. Patients with a dilated bile duct and delayed drainage of contrast material as demonstrated at endoscopic retrograde cholangiopancreatography (ERCP) had a more favorable response to sphincterotomy than those with normal ductal findings (p = 0.01). There was a higher complication rate in those without ductal dilation and delayed drainage compared to those with these ERCP abnormalities (p = 0.03). Sphincter of Oddi manometry was obtained in 29 patients prior to sphincterotomy; 24 were available for follow-up. A favorable outcome for sphincterotomy did not correlate with manometric assessment, particularly in patients with an abnormal ductal system.
对51例因怀疑Oddi括约肌功能障碍而接受内镜括约肌切开术的患者进行了回顾性评估。该手术使疼痛完全消除，46例可供随访的患者中有31例停用了镇痛药。在内镜逆行胰胆管造影（ERCP）中显示胆管扩张和造影剂引流延迟的患者，对括约肌切开术的反应比胆管检查结果正常的患者更有利（p = 0.01）。与有这些ERCP异常的患者相比，没有胆管扩张和引流延迟的患者并发症发生率更高（p = 0.03）。29例患者在括约肌切开术前进行了Oddi括约肌测压；24例可供随访。括约肌切开术的良好结果与测压评估无关，特别是在胆管系统异常的患者中。
