Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Int J Neurosci. 2023 Dec;133(12):1309-1314. doi: 10.1080/00207454.2022.2079499. Epub 2022 Jun 13.
Spinal giant cell tumor (GCT) combined with secondary aneurysmal bone cyst (ABC) is a locally aggressive primary bone tumor. Total en bloc spondylectomy has never been reported to treat thoracic GCT combined with secondary ABC. We retrospectively reviewed two cases of spinal GCT combined with secondary ABC. A 41-year-old male patient was presented with back pain due to irregular expansive bone destruction involving the T6 vertebral body and intraspinal space-occupying lesion. Total en bloc spondylectomy of T6 vertebra was performed with good neurological status after the surgery. A 29-year-old female patient was presented with right scapular region pain due to irregular expansive bone destruction involving the T5 vertebral body and intraspinal space-occupying lesion. Total en bloc spondylectomy of T5 vertebra was performed with good neurological status after the surgery. Adjuvant radiation therapy was applied after the surgery without local recurrence at the 12-month or 24-month follow-up. Spinal GCT combined with secondary ABC appears to have a high local recurrence rate. Therefore, total en bloc spondylectomy should be applied to treat thoracic GCT combined with secondary ABC.
脊柱巨细胞瘤（GCT）合并继发性动脉瘤样骨囊肿（ABC）是一种局部侵袭性原发性骨肿瘤。全脊椎整块切除术从未被报道用于治疗胸段 GCT 合并继发性 ABC。我们回顾性分析了 2 例脊柱 GCT 合并继发性 ABC 的病例。1 例 41 岁男性患者因 T6 椎体不规则膨胀性骨破坏伴椎管内占位病变导致背痛。行 T6 椎体整块全脊椎切除术，术后神经功能良好。1 例 29 岁女性患者因 T5 椎体不规则膨胀性骨破坏伴椎管内占位病变导致右肩胛区疼痛。行 T5 椎体整块全脊椎切除术，术后神经功能良好。术后行辅助放疗，12 个月和 24 个月随访均未见局部复发。脊柱 GCT 合并继发性 ABC 局部复发率较高。因此，全脊椎整块切除术应作为治疗胸段 GCT 合并继发性 ABC 的首选方法。
