Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Dushu Lake Campus, Suzhou 215123, People's Republic of China.
J Org Chem. 2022 Jul 1;87(13):8757-8763. doi: 10.1021/acs.joc.2c00389. Epub 2022 Jun 14.
The selective reduction of quinolin-2(1)-ones promoted by a SmI/HO/MeOH system is reported for the first time. The reaction is effectively carried out to afford 3,4-dihydroquinoline-2(1)-ones under mild conditions in a one-pot fashion with good to excellent yields.
首次报道了 SmI/HO/MeOH 体系促进的喹啉-2(1H)-酮的选择性还原。该反应在温和条件下以一锅法有效地进行，以良好至优异的收率得到 3,4-二氢喹啉-2(1H)-酮。
