[Complex medico-genetic study of the Western Siberian population. II. Population-genetic study of fluorescent chromosome polymorphism in Northern Khanty].

Polymorphisms of fluorescent variants of 469 human karyotypes from five subpopulations of the Northern Khanty were studied. Significant frequency variability of Q-polymorphic variants of chromosomes was shown. Wahlund's variance for 12 chromosome polymorphic segments was 0.0121, while the total inbreeding coefficient was 0.0069 with a negative nonrandom component. Heterozygosity estimated for chromosome fluorescent polymorphism (0.189) agrees well with that for blood group systems and less for enzymes. The frequencies of Q-polymorphic variants corresponded to Hardy-Weinberg equilibrium, except for chromosome 13 which gave the significant excess of heterozygotes. Possible explanations of this phenomenon are discussed.