Noguchi H, Shiozawa I, Sakai Y, Yamazaki T, Fukuta T
Gynecol Oncol. 1987 Jun;27(2):150-8. doi: 10.1016/0090-8258(87)90287-3.
The state of pelvic lymph node metastasis was observed in 627 cases of Okabayashi's radical hysterectomy performed from 1950 to 1984 of which 589 cases with a known 5-year survival rate were examined according to their relationship to prognosis. The incidence of lymph node metastasis was 29.7%, becoming progressively higher with succeeding clinical stages. The metastasis rates according to site were 6.9% hypogastric nodes, 4.9% obturator nodes, 4.4% iliac nodes, and 25.0% parametrial nodes. Among the factors considered in the postoperative classification, lymph node metastasis demonstrated high values in cervical infiltration cancer, positive parametrial infiltration, positive vaginal invasion, and infiltration into the uterine body and L type of CPL classification. The 5-year survival rate was 83.0% in negative cases of pelvic lymph node metastasis, while in positive cases, it was as poor as 45.8%. Considering the relationship of various factors, it is shown that the presence of lymph node metastasis has a great effect on prognosis.
观察了1950年至1984年间行冈林式子宫根治术的627例患者盆腔淋巴结转移情况,其中589例已知5年生存率,并根据其与预后的关系进行了检查。淋巴结转移发生率为29.7%,随着临床分期的增加而逐渐升高。根据部位的转移率分别为:下腹淋巴结6.9%,闭孔淋巴结4.9%,髂淋巴结4.4%,宫旁淋巴结25.0%。在术后分类所考虑的因素中,淋巴结转移在宫颈浸润癌、宫旁浸润阳性、阴道浸润阳性、子宫体浸润以及CPL分类的L型中显示出较高的值。盆腔淋巴结转移阴性患者的5年生存率为83.0%,而阳性患者的5年生存率低至45.8%。考虑到各种因素的关系,表明淋巴结转移的存在对预后有很大影响。