Department of Dermatology, All India Institute of Medical Sciences, Raipur, Chhattisgarh 492099, India.
Curr Drug Saf. 2023 Apr 27;18(4):584-588. doi: 10.2174/1574886317666220613163327.
There have been increasing reported cases of new-onset or aggravation of pre-existing dermatoses after the implementation of COVID-19 vaccination.
An elderly male was presented with multiple annular scaly plaques all over the body two weeks following administration of the first dose of Oxford-AstraZeneca COVID-19 vaccine. The lesions further aggravated after taking the second dose of the vaccine. The clinical and histopathology features were suggestive of annular plaque psoriasis.
We report this first case of de novo plaque psoriasis following the Oxford- AstraZeneca COVID-19 vaccine, and it signifies a potential side effect of autoimmune reactivation after COVID vaccination.
在实施 COVID-19 疫苗接种后，新出现或原有皮肤病恶化的报告病例不断增加。
一名老年男性在接种第一剂牛津-阿斯利康 COVID-19 疫苗两周后，全身出现多个环状鳞屑斑块。接种第二剂疫苗后，皮损进一步加重。临床和组织病理学特征提示环状斑块型银屑病。
我们报告了首例牛津-阿斯利康 COVID-19 疫苗接种后新发斑块型银屑病病例，这表明 COVID 疫苗接种后可能存在自身免疫再激活的潜在副作用。
