Additional Professor, Department of Orthopaedics, AIIMS Jodhpur, Jodhpur, Rajasthan, 342005, India.
Senior Resident, Department of Orthopaedics, AIIMS Jodhpur, Jodhpur, Rajasthan, 342005, India.
Regen Med. 2022 Sep;17(9):617-626. doi: 10.2217/rme-2022-0009. Epub 2022 Jun 15.
Mucoid degeneration of the anterior cruciate ligament (ACL) is commonly treated with arthroscopic debridement of the ACL. But many studies have reported the weakening and laxity of ACL postoperatively and on follow-up. Platelet-rich plasma (PRP) is known to influence musculoskeletal healing through multiple growth factors. Five patients who were diagnosed as a case of mucoid degeneration of the ACL based on MRI, over a period of 1 year (December 2018-2019), were included in the study. Autologous PRP, prepared by double spin protocol, was injected into the remaining ACL after partial debridement was done. Visual analogue scale and Lysholm scores improved compared with preoperative scores, along with strength (anterior drawer test and Lachman test). PRP can be used to improve the healing and strength of a weakened ACL after partial debridement, but further research is needed to demonstrate its efficacy.
前交叉韧带（ACL）黏液样变性通常采用关节镜下 ACL 清创术进行治疗。但是，许多研究报告指出术后和随访时 ACL 会出现减弱和松弛。富血小板血浆（PRP）已知通过多种生长因子影响肌肉骨骼愈合。 本研究纳入了 5 名患者，这些患者均根据 MRI 诊断为 ACL 黏液样变性病例，时间跨度为 1 年（2018 年 12 月至 2019 年）。在进行部分清创后，将通过双旋协议制备的自体 PRP 注入剩余的 ACL 中。与术前评分相比，视觉模拟评分和 Lysholm 评分均有所改善，同时还改善了力量（前抽屉试验和lachman 试验）。PRP 可用于改善部分清创后减弱的 ACL 的愈合和强度，但需要进一步的研究来证明其疗效。
