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一个沙漠国家儿童的哮喘与血清免疫球蛋白E水平

Asthma and serum IgE levels in children in a desert country.

作者信息

Strannegård I L, Strannegård O

出版信息

Int Arch Allergy Appl Immunol. 1987;82(3-4):553-4. doi: 10.1159/000234278.

DOI:10.1159/000234278
PMID:3570524
Abstract

The frequency of asthma admissions to the paediatric outpatient clinic in a teaching hospital in Kuwait was found to increase from 8.8 to 14.9% of all admissions during a 3-year period. Seasonal variation of admissions was consistent, with peak incidences during the cold and humid months. The incidence of asthma was remarkably well correlated to low temperature and high frequency of upper respiratory infections but not to pollen seasons or occurrence of dust storms. In agreement with the clinical impression that atopic allergy is frequent in Kuwait, high levels of IgE were found in different groups of individuals. In umbilical cord serum, elevated IgE levels in blood donors and in children with asthma or other diseases were clearly higher than those found in corresponding groups in Western countries. Possible factors contributing to the generally increased IgE levels may be endemic diseases, like viral hepatitis and brucellosis.

摘要

科威特一家教学医院儿科门诊哮喘入院病例数在3年期间占总入院病例数的比例从8.8%增至14.9%。入院病例存在季节性变化规律,寒冷潮湿月份发病率最高。哮喘发病率与低温及上呼吸道感染高发显著相关,与花粉季节或沙尘暴发生情况无关。与科威特特应性过敏常见的临床印象一致,不同人群中均发现IgE水平较高。在脐带血血清、献血者以及患有哮喘或其他疾病的儿童中,IgE水平明显高于西方国家相应人群。导致IgE水平普遍升高的可能因素或许是地方性疾病,如病毒性肝炎和布鲁氏菌病。

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Asthma and serum IgE levels in children in a desert country.一个沙漠国家儿童的哮喘与血清免疫球蛋白E水平
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