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Synthesis of new head-activator analogues and their application for improved radioimmunoassays.

作者信息

Bodenmüller H, Escher E, Zachmann B, Schilling E

出版信息

Int J Pept Protein Res. 1987 Jan;29(1):140-4. doi: 10.1111/j.1399-3011.1987.tb02240.x.

Abstract

New analogues of head activator were produced for receptor and radioimmunoassay studies. The precursor molecules [(4'-I)Phe11] head activator and [Tyr11] head activator were synthesised for catalytic tritiation and iodination, respectively. With the tracer [(3,5-125 I2)Tyr11] head activator the sensitivity range of the radioimmunoassay was 5-100 fmol.

摘要

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