Two new amides from the seeds of var. lacryma-jobi.

Phytochemical investigation of the seeds of var. lacryma-jobi resulted in the isolation of eight compounds, including two new structures, coixdines A-B () and six known compounds (). The structures of these compounds were determined by 1 D and 2 D NMR spectra referring to the literatures, together with HR-MS analysis. Coixdine A and B are first examples of spermidine skeleton in genus . In the present paper, all compounds were evaluated for the cytotoxicity against two cancer cell lines (CT-26 and BxPC-3) , and none of the compounds exhibited obvious cytotoxic activity. The present investigation suggests that these amides seem to be of great chemotaxonomic value for .