Division of Plastic Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
Eur J Cancer Care (Engl). 2022 Jul;31(4):e13631. doi: 10.1111/ecc.13631. Epub 2022 Jun 16.
Women diagnosed with breast cancer are receiving mastectomy with implant-based reconstruction at an increasing rate. Chronic post-surgical pain can be a major concern for these patients. This review sought to address the knowledge gap on the prevalence, severity and characteristics of chronic pain in this population.
A scoping review was conducted using the Arksey and O'Malley framework. Five databases were searched using keywords. Two independent reviewers performed selection and data extraction of studies that met inclusion criteria.
Seventeen studies were included in this review. Ten studies reported prevalence of chronic pain which ranged from 7.3%-90.9% with pooled prevalence of 26.3%. Nine studies reported severity of chronic pain using various scales and methodology; most patients' pain was not severe. Risk factors for chronic pain included axillary dissection, lack of perioperative local anaesthetic, younger age and use of a tissue expander. No studies reported on possible correlation between ethnicity and pain. Eleven different assessment tools were used to measure pain.
Chronic pain following post-mastectomy implant-based breast reconstruction is prevalent, associated with specific risk factors and poorly characterised. There is a need to investigate and evaluate chronic pain in this population using validated breast cancer specific pain assessment tools.
越来越多被诊断患有乳腺癌的女性选择接受乳房切除术和基于植入物的重建。慢性术后疼痛可能是这些患者的主要关注点。本综述旨在解决该人群中慢性疼痛的流行率、严重程度和特征的知识空白。
使用 Arksey 和 O'Malley 框架进行了范围综述。使用关键词在五个数据库中进行了搜索。两名独立的审查员对符合纳入标准的研究进行了选择和数据提取。
本综述纳入了 17 项研究。10 项研究报告了慢性疼痛的流行率,范围从 7.3%到 90.9%,总流行率为 26.3%。9 项研究使用各种量表和方法报告了慢性疼痛的严重程度;大多数患者的疼痛并不严重。慢性疼痛的危险因素包括腋窝清扫术、缺乏围手术期局部麻醉、年龄较小和使用组织扩张器。没有研究报告种族与疼痛之间可能存在相关性。11 种不同的评估工具用于测量疼痛。
乳房切除术和基于植入物的乳房重建后慢性疼痛很常见,与特定的危险因素有关,且特征描述较差。有必要使用经过验证的乳腺癌特异性疼痛评估工具来研究和评估该人群中的慢性疼痛。