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2020 年 3 月至 2022 年 4 月期间巴西南部的 COVID-19 大流行:住院、重症监护病房入院、死亡率和住院时间。

COVID-19 pandemic in Southern Brazil: Hospitalizations, intensive care unit admissions, lethality rates, and length of stay between March 2020 and April 2022.

机构信息

Value Management Office, Medical Manager at Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.

Medical Manager, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.

出版信息

J Med Virol. 2022 Oct;94(10):4839-4849. doi: 10.1002/jmv.27942. Epub 2022 Jun 23.

Abstract

Coronavirus disease 2019 (COVID-19) pandemic spread rapidly with more than 515 million cases and 6.2 million deaths. Epidemiological factors are important for understanding the state of the pandemic. This study aims to evaluate the hospitalizations, intensive care unit (ICU) admissions, and lethality from March 2020 to April 2022. Data were collected from a hospital in Porto Alegre city, southern Brazil. The Mann-Whitney, analysis of variance, and Kruskal-Wallis tests were used to compare quantitative variables. Categorical variables were compared by Pearson's χ test. p values <0.05 for all tests were considered significant. Were observed 3784 hospitalizations. Males were 51.4% and the age was 60.4± 20.3. Intensive care unit (ICU) patients were 31.2%, the median length of stay (LOS) was 9.0 and lethality was 13.3%. ICU lethality was 34.5% versus 4.6% in other inpatients (p < 0.01). The LOS of ICU patients was 22.0 versus 7.0 in other inpatients (p < 0.01). The first peak (July-Novemebr 2020) showed ICU occupancy of 79.1%. The second peak (December 2020-June 2021) with 91.6% occupancy. The third peak January-March 2022 with 81.0% occupancy (p < 0.01). Lethality rates were 10.3% in 2020, 14.9% in 2021 and 15.4% in 2022 (p < 0.01). In conclusion, the ICU occupancy rate was higher in 2021 and the lethality rates of ICU patients were high during pandemic years (10.3% in 2020, 14.9% in 2021, and 15.2% in 2022). The lethality of these patients ranged from 25.0% in March to 21.8% in December 2020, from 20.9% in January 22.2% in Decemebr 2021, and 35.7% in January 2022 to 21.4% in April 2022. These data demonstrate that COVID-19 is a critical illness, even in a private hospital setting.

摘要

2019 年冠状病毒病(COVID-19)大流行迅速蔓延,全球确诊病例超过 5.15 亿例,死亡病例超过 620 万例。流行病学因素对于了解大流行状况很重要。本研究旨在评估 2020 年 3 月至 2022 年 4 月期间的住院、重症监护病房(ICU)入住和病死率。数据来自巴西南部阿雷格里港的一家医院。采用 Mann-Whitney、方差分析和 Kruskal-Wallis 检验比较定量变量。使用 Pearson's χ 检验比较分类变量。所有检验的 p 值均<0.05 被认为具有统计学意义。共观察到 3784 例住院患者。男性占 51.4%,年龄为 60.4±20.3 岁。入住 ICU 的患者占 31.2%,中位住院时间(LOS)为 9.0 天,病死率为 13.3%。ICU 病死率为 34.5%,而其他住院患者为 4.6%(p<0.01)。ICU 患者的 LOS 为 22.0 天,而其他住院患者为 7.0 天(p<0.01)。第一个高峰(2020 年 7 月至 11 月)显示 ICU 入住率为 79.1%。第二个高峰(2020 年 12 月至 2021 年 6 月)为 91.6%。第三个高峰(2022 年 1 月至 3 月)为 81.0%(p<0.01)。2020 年病死率为 10.3%,2021 年为 14.9%,2022 年为 15.4%(p<0.01)。总之,2021 年 ICU 入住率较高,大流行期间 ICU 患者病死率较高(2020 年为 10.3%,2021 年为 14.9%,2022 年为 15.4%)。这些患者的病死率范围为 2020 年 3 月的 25.0%至 12 月的 21.8%,2021 年 1 月的 20.9%至 12 月的 22.2%,2022 年 1 月的 35.7%至 4 月的 21.4%。这些数据表明,即使在私立医院环境中,COVID-19 也是一种严重疾病。

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