Department of Emergency Medicine, UC Davis, Sacramento, CA, USA.
Department of Pediatrics, Division of Hematology and Oncology, UC Davis, Sacramento, CA, USA.
Am J Emerg Med. 2022 Sep;59:217.e1-217.e3. doi: 10.1016/j.ajem.2022.06.024. Epub 2022 Jun 12.
Acute lymphocytic leukemia (ALL) is a common pediatric cancer diagnosis with excellent survival outcomes but significant morbidity, particularly during the induction phase of chemotherapy. Central venous sinus thrombosis (CVST) is a known potential complication of induction therapy; however, it occurs rarely and may be difficult to diagnose, particularly in young children who have limited verbal skills. Herein, we report a case of CVST in a child with B-cell ALL undergoing induction chemotherapy whose main symptoms were headache and a change in the appearance of his artwork noticed by his parents. This astute observation by the child's parents played a critical role in his diagnosis, allowing prompt treatment and eventual recovery.
急性淋巴细胞白血病（ALL）是一种常见的儿科癌症诊断，具有极好的生存结果，但发病率很高，尤其是在化疗诱导期。中心静脉窦血栓形成（CVST）是诱导治疗的已知潜在并发症；然而，它很少发生，并且可能难以诊断，特别是在语言能力有限的幼儿中。在此，我们报告了一例接受诱导化疗的 B 细胞 ALL 患儿发生 CVST 的病例，其主要症状是头痛和父母注意到的艺术品外观改变。患儿父母的这种敏锐观察在其诊断中发挥了关键作用，使他得到了及时治疗并最终康复。
