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大鼠膝关节感觉神经末梢分布的放射自显影研究。

An autoradiographic study of the distribution of sensory nerve endings in the knee joint of the rat.

作者信息

Kanatani Y, Hirohata K, Umetani T

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1986 Dec;60(12):1283-92.

PMID:3572134
Abstract

The distribution of sensory nerve endings of the knee joint in rats has been investigated by autoradiography of 3H-leucine. Sections were made and each section was examined by autoradiography and silver impregnation staining. Free nerve endings were found only in the synovial membrane, the menisci and their synovial junction. In the joint capsule, capsulated sensory nerve endings were sparsely distributed. Numerous sensory nerve endings were found at the insertion of the patellar ligament, the collateral ligament and the cruciate ligament. These resembling Golgi-Mazzoni nerve endings or capsulated sensory nerve endings are thought to be proprioceptors. Radioactivity, which would indicate the presence of sensory nerve endings, was not recognized in the osseous tissue. It is hypothesized that proprioceptor at the insertion of ligaments plays an important role as monitor of joint motion by the reflex pathway.

摘要

通过对3H-亮氨酸进行放射自显影,研究了大鼠膝关节感觉神经末梢的分布情况。制作切片,然后对每片切片进行放射自显影和银浸染染色检查。仅在滑膜、半月板及其滑膜连接处发现了游离神经末梢。在关节囊中,被囊感觉神经末梢分布稀疏。在髌韧带、侧副韧带和交叉韧带的附着处发现了大量感觉神经末梢。这些类似于高尔基-马佐尼神经末梢或被囊感觉神经末梢的结构被认为是本体感受器。在骨组织中未检测到表明感觉神经末梢存在的放射性。据推测,韧带附着处的本体感受器通过反射通路作为关节运动的监测器发挥重要作用。

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