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确诊 COVID-19 患者中慢性肾脏病与死亡率的相关性。

Association between chronic kidney disease and mortality in patients with a confirmed COVID-19 diagnosis.

机构信息

Sociedad Científica de Estudiantes de Medicina, SOCIEM-UNPRG, Universidad Nacional Pedro Ruiz Gallo, Lambayeque, Perú.

Universidad Continental, Huancayo, Perú.

出版信息

PeerJ. 2022 Jun 14;10:e13437. doi: 10.7717/peerj.13437. eCollection 2022.

DOI:10.7717/peerj.13437
PMID:35722260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9205307/
Abstract

OBJECTIVE

To determine the association between chronic kidney disease (CKD) and mortality in persons with a confirmed coronavirus disease 2019 (COVID-19) diagnosis.

METHODS

Cross-sectional secondary baseline study. The study population consisted of 243,065 patients confirmed to have COVID-19 during May-December 2020. Stata 16.0 was used for statistical analysis, Chi-square test was used for bivariate analysis, and Poisson regression with robust variances was used for multiple analysis.

RESULTS

The prevalence of patients with a confirmed COVID-19 diagnosis who had CKD and died was 1.42 times the prevalence of mortality in those without CKD. The comorbidities combined with CKD that presented the highest probability of mortality were diabetes mellitus and hypertension.

CONCLUSIONS

CKD is associated with a high mortality rate in patients with a confirmed COVID-19 diagnosis. Patients with CKD, diabetes mellitus, and arterial hypertension have a higher prevalence of mortality than those without comorbidities.

摘要

目的

确定确诊 2019 年冠状病毒病(COVID-19)患者中慢性肾脏病(CKD)与死亡率之间的关联。

方法

横断面二次基线研究。研究人群由 2020 年 5 月至 12 月期间确诊为 COVID-19 的 243065 例患者组成。使用 Stata 16.0 进行统计分析,使用卡方检验进行双变量分析,使用稳健方差的泊松回归进行多变量分析。

结果

确诊 COVID-19 诊断且患有 CKD 并死亡的患者的患病率是无 CKD 患者死亡率的 1.42 倍。与 CKD 合并的合并症中,糖尿病和高血压的死亡率最高。

结论

CKD 与确诊 COVID-19 患者的高死亡率相关。患有 CKD、糖尿病和动脉高血压的患者比没有合并症的患者死亡率更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34b/9205307/b24709cbffd6/peerj-10-13437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34b/9205307/b24709cbffd6/peerj-10-13437-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34b/9205307/b24709cbffd6/peerj-10-13437-g001.jpg

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