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回顾性数据库分析 2019 冠状病毒病大流行期间社交隔离前后与儿科感染率和医疗保健服务使用的关系。

A Retrospective Database Analysis of Before and After Social Distancing in Relation to Pediatric Infection Rate and Healthcare Services Usage During the Coronavirus Disease 2019 Pandemic.

机构信息

Maccabi Healthcare Services, Israel.

Ruth and Bruce Rappaport Faculty of Medicine, Technion University, Haifa, Israel.

出版信息

Clin Infect Dis. 2023 Feb 18;76(4):713-719. doi: 10.1093/cid/ciac502.

Abstract

BACKGROUND

Social distancing policy was introduced in Israel in 2020 to reduce the spread of coronavirus disease 2019 (COVID-19). The aim of this study was to analyze the effect of social distancing on other infections in children, by comparing disease rate and healthcare utilization before and after social distancing.

METHODS

This was a before-and-after study. Within this retrospective database analysis of parallel periods in 2019 (periods 1 and 2) and 2020 (periods 3 [prelockdown period] and 4 [lockdown period]) we included all pediatric population registered in the electronic medical records of the Maccabi Healthcare Services, Israel, looking at the occurrence of non-COVID-19 infections, antibiotic purchasing, physician visits, ambulatory emergency care center visits, emergency department visits, and hospitalizations.

RESULTS

A total of 776 828 children were included from 2019, and 777 729 from 2020. We found a lower infection rate in 2020 versus 2019. We did not find a difference in infection rate between periods 1 and 2, while there was a significant difference between periods 3 and 4. We found a significant difference between periods 2 and 4, with a higher RR than for the comparison between periods 1 and 3. There was a modest decrease in ambulatory emergency care center visits in 2020, and lower increases in emergency department visits and hospital admissions. We found decreases in antibiotic purchasing between periods 1 and 3 and between periods 2 and 4, more pronounced in 2020 than in 2019.

CONCLUSIONS

Analysis of findings before and after social distancing and masking showed reduced prevalence of non-COVID-19 pediatric infections and reduced consumption of healthcare services and antibiotics related with the lockdown period.

摘要

背景

社交距离政策于 2020 年在以色列推出,以减少 2019 年冠状病毒病(COVID-19)的传播。本研究的目的是通过比较社交距离政策前后的疾病发生率和医疗保健利用情况,分析社交距离政策对儿童其他感染的影响。

方法

这是一项前后对照研究。在 2019 年(第 1 期和第 2 期)和 2020 年(第 3 期[封锁前]和第 4 期[封锁期])的平行期间内,我们对电子病历中的所有儿科人群进行了回顾性数据库分析,观察非 COVID-19 感染、抗生素购买、医生就诊、门诊急救中心就诊、急诊就诊和住院的发生情况。

结果

共纳入 2019 年 776828 例儿童和 2020 年 777729 例儿童。我们发现 2020 年的感染率低于 2019 年。我们没有发现第 1 期和第 2 期之间的感染率差异,而第 3 期和第 4 期之间存在显著差异。我们发现第 2 期和第 4 期之间存在显著差异,与第 1 期和第 3 期之间的比较相比,RR 值更高。2020 年门诊急救中心就诊次数略有减少,急诊就诊和住院人数增加幅度较低。我们发现第 1 期和第 3 期之间以及第 2 期和第 4 期之间抗生素购买量减少,2020 年比 2019 年更为明显。

结论

社交距离和口罩政策前后的分析结果表明,非 COVID-19 儿科感染的流行率降低,与封锁期相关的医疗保健服务和抗生素的使用量减少。

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