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[浙江省绍兴市上虞区2019新型冠状病毒Delta变异株所致新型冠状病毒肺炎的流行病学特征]

[Epidemiological characteristics of COVID-19 caused by 2019-nCoV Delta variant in Shangyu district, Shaoxing of Zhejiang province].

作者信息

Wu Y Y, Wang Z, Chai C L, He F, Ling F, Pan J, Li F D, Cheng W, Liu K, Zhang Y, Zhang G M, Yu M

机构信息

Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.

Jinhua Prefectural Center for Disease Control and Prevention, Jinhua 321000, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2022 Jun 10;43(6):846-851. doi: 10.3760/cma.j.cn112338-20220128-00087.

Abstract

To investigate the epidemiological characteristics of COVID-19 caused by 2019-nCoV Delta variant in Shangyu district, Shaoxing of Zhejiang province in 2021, and provide evidence for the improvement of COVID-19 control and prevention measures. The incidence data of COVID-19 in Shangyu from December 7 to 21, 2021 was obtained from Shangyu District Center for Disease Control and Prevention. The epidemiological characteristics of the cases, i.e. the population, time and space distributions, were analyzed, and the incubation period and time-varying reproduction numbers () were calculated. From December 7 to 21, 2021, a total of 380 COVID-19 cases caused by 2019-nCoV Delta variant were detected in Shangyu, the median age of the cases was 52 years, (: 38, 61). The male to female ratio of the cases was 1∶1.25, and the cases were mainly workers (36.58%) and farmers (27.63%). The epidemic affected 9 townships (or community) of Shangyu, especially Caoe and Baiguan communities with the cases accounting for 57.10% and 31.53% respectively. The median incubation period of cases was 4.00 days, (: 3.00, 5.75). The basic reproduction number () was 4.06, and the was 5.62 in early phase of the outbreak (the highest) and continuously decreased to less than 1.00 within 10 days after the detection of the outbreak. The number of COVID-19 cases decreased to 0 within 14 days after the outbreak (December 7-21), and the main detection methods were screening in centralized isolation (55.53%) and home isolation (40.00%). The infection rates of close contacts and secondary close contacts were 2.06% and 0.46% respectively. The epidemic of COVID-19 in Shangyu characterized by short incubation period, large number of infected people, and case clustering, suggesting the strong transmission of Delta variant (B.1.617.2). Comprehensive prevention and control measures, such as management of close contacts and secondary close contacts, and high-risk area, are essential for the rapid control of the epidemic.

摘要

为调查2021年浙江省绍兴市上虞区新型冠状病毒(2019-nCoV)德尔塔变异株引起的新型冠状病毒肺炎(COVID-19)的流行病学特征,为完善COVID-19防控措施提供依据。上虞区疾病预防控制中心提供了2021年12月7日至21日上虞区COVID-19的发病数据。分析了病例的流行病学特征,即人群、时间和空间分布,并计算了潜伏期和时间变化的传播指数()。2021年12月7日至21日,上虞区共检测到380例由2019-nCoV德尔塔变异株引起的COVID-19病例,病例的中位年龄为52岁(四分位数间距:38,61)。病例的男女比例为1∶1.25,病例主要为工人(36.58%)和农民(27.63%)。疫情波及上虞区9个乡镇(或社区),尤以曹娥和百官社区受影响较大,病例分别占57.10%和31.53%。病例的中位潜伏期为4.00天(四分位数间距:3.00,5.75)。基本传播指数()为4.06,疫情初期(最高)的为5.62,并在疫情发现后10天内持续下降至低于1.00。疫情发生后(12月7日至21日)14天内COVID-19病例数降至0,主要检测方式为集中隔离筛查(55.53%)和居家隔离(40.00%)。密切接触者和次密切接触者的感染率分别为2.06%和0.46%。上虞区COVID-19疫情具有潜伏期短、感染人数多、病例聚集的特点,提示德尔塔变异株(B.1.617.2)传播力强。对密切接触者、次密切接触者以及高风险地区等采取综合防控措施,对于迅速控制疫情至关重要。

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