Liu J, Guo C, Zhou Wei
Institute of Population Research, Peking University, Beijing 100871, China.
Institute of Population Research, Peking University, Beijing 100871, China Asia-Pacific Economic Cooperation Health Science Academy, Peking University, Beijing 100871, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2022 Jun 10;43(6):898-905. doi: 10.3760/cma.j.cn112338-20210810-00628.
To explore the effect of childhood living environment sanitation on the prevalence of chronic diseases in middle-aged and elderly rural residents and test the mediating product of childhood health status. Based on the data of 12 506 rural residents jointly interviewed by the latest survey of China Health and Retirement Longitudinal Survey (CHARLS) in 2018 and the life course survey in 2014, the test, Rank sum test, logistic regression analysis model, Propensity score weighting method, negative binomial regression model and KHB analysis method were used for analysis. After adjusting for other confounding factors, compared with rural residents with better living environment sanitation in childhood, the risk of asthma in middle-aged and elderly rural residents with poor childhood living environment sanitation increased by 23.7% (=1.237,95% 1.060-1.445), and the risk of liver disease, kidney disease, and digestive system disease increased by 16.4% (=1.164,95% 1.006-1.347) and 22.4% (=1.224,95% 1.083-1.383) and 19.6% (=1.196,95% 1.103-1.296), the possibility of dyslipidemia and heart disease increased by 26.6% (=1.266,95% 1.153-1.390) and 13.6% (=1.136,95% 1.031-1.253). The negative binomial regression model analysis results show that, on average, the number of chronic diseases of middle-aged and elderly rural residents with poor living environment sanitation in childhood is 0.176 more than that of middle-aged and elderly rural residents with better living environment sanitation in childhood. Childhood health status played an intermediary role of 7.143%. There is a statistical correlation between residential environmental sanitation in childhood and the prevalence and number of chronic diseases in middle-aged and elderly rural residents. Childhood health status plays a partial intermediary role. Attention should be paid to the construction and management of rural residents' residential environment to provide a clean and hygienic growth environment for children and adolescents to promote the health of rural residents in the whole life cycle.
探讨农村中老年居民童年生活环境卫生状况对其慢性病患病率的影响，并检验童年健康状况的中介作用。基于中国健康与养老追踪调查（CHARLS）2018年最新调查与2014年生命历程调查联合访谈的12506名农村居民的数据，采用检验、秩和检验、logistic回归分析模型、倾向得分加权法、负二项回归模型及KHB分析方法进行分析。在调整其他混杂因素后，与童年生活环境卫生状况较好的农村居民相比，童年生活环境卫生状况较差的农村中老年居民患哮喘的风险增加了23.7%（=1.237，95%置信区间1.060 - 1.445），患肝病、肾病和消化系统疾病的风险分别增加了16.4%（=1.164，95%置信区间1.006 - 1.347）、22.4%（=1.224，95%置信区间1.083 - 1.383）和19.6%（=1.196，95%置信区间1.103 - 1.296），患血脂异常和心脏病的可能性分别增加了26.6%（=1.266，95%置信区间1.153 - 1.390）和13.6%（=1.136，95%置信区间1.031 - 1.253）。负二项回归模型分析结果显示，平均而言，童年生活环境卫生状况较差的农村中老年居民患慢性病的数量比童年生活环境卫生状况较好的农村中老年居民多0.176种。童年健康状况起到了7.143%的中介作用。童年居住环境卫生与农村中老年居民慢性病患病率及患病数量之间存在统计学关联。童年健康状况起到部分中介作用。应重视农村居民居住环境的建设与管理，为儿童和青少年提供清洁卫生的成长环境，以促进农村居民全生命周期的健康。
