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医疗机构多学科工作组实施 HIV 暴露前预防(PrEP)前后的指标。

Metrics of HIV Pre-exposure Prophylaxis (PrEP) Implementation Before and After a Multidisciplinary Task Force at an Academic Institution.

机构信息

Division of Infectious Diseases, University of Pennsylvania, Philadelphia (Drs Liu, Short, and Koenig); and Indian Health Service, Chinle, Arizona, and University of Pennsylvania Perelman School of Medicine, Philadelphia (Dr Stewart).

出版信息

Qual Manag Health Care. 2022;31(3):170-175. doi: 10.1097/QMH.0000000000000332. Epub 2021 Oct 18.

DOI:10.1097/QMH.0000000000000332
PMID:35727768
Abstract

BACKGROUND AND OBJECTIVES

There is a paucity of guidance on HIV pre-exposure prophylaxis (PrEP) implementation in an academic medical center. The objectives of this study were to describe interventions by a multidisciplinary PrEP task force at an academic medical center and compare metrics of PrEP implementation pre- and post-creation of this entity.

METHODS

The interventions of the task force are described within the rubric of the PrEP care continuum. Participants were adults prescribed PrEP for greater than or equal to 30 days at 9 clinical sites across a university health system. Metrics of PrEP implementation were compared over 12-month intervals before and after the creation of the task force.

RESULTS

An increased proportion of participants had HIV testing within 7 days of new PrEP prescriptions (92% vs 63%, P < .001) and were prescribed PrEP in increments of 90 days or shorter (74% vs 56%, P < .001) after the creation of the task force. There were higher rates of testing for bacterial sexually transmitted infections in men who had sex with men and transgender women in the post-intervention compared with pre-intervention period.

CONCLUSIONS

A multidisciplinary team that focuses on optimizing PrEP delivery along each step of the care continuum may facilitate PrEP scale-up and best practices in an academic setting.

摘要

背景与目的

在学术医疗中心,关于艾滋病毒暴露前预防(PrEP)实施的指导很少。本研究的目的是描述学术医疗中心多学科 PrEP 工作组的干预措施,并比较创建该实体前后 PrEP 实施的指标。

方法

工作组的干预措施在 PrEP 护理连续体的范围内进行描述。参与者为在大学健康系统的 9 个临床地点接受 PrEP 治疗超过 30 天的成年人。在创建工作组前后的 12 个月间隔内比较 PrEP 实施的指标。

结果

与创建工作组之前相比,更多的参与者在新的 PrEP 处方后 7 天内进行了 HIV 检测(92% 比 63%,P <.001),并且更短时间(74% 比 56%,P <.001)开具 PrEP 处方。在干预后,与干预前相比,男男性行为者和跨性别女性中细菌性性传播感染的检测率更高。

结论

专注于优化 PrEP 治疗每个步骤的多学科团队可能有助于在学术环境中扩大 PrEP 规模并采用最佳实践。

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