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Evidence for phosphorylation of the extracellular acid phosphatase of Leishmania donovani.

作者信息

Lovelace J K, Gottlieb M

出版信息

J Protozool. 1987 Feb;34(1):78-9. doi: 10.1111/j.1550-7408.1987.tb03136.x.

DOI:10.1111/j.1550-7408.1987.tb03136.x
PMID:3572843
Abstract

The presence of two phosphorylated molecular species in the culture supernatants of axenically cultivated Leishmania donovani promastigotes was demonstrated by biosynthetically labeling cultures with [32P]phosphate. One of these species was resolved into two bands with Mr's of 149,000 and 97,000 by dissociating polyacrylamide gel electrophoresis and copurified with the extracellular acid phosphatase activity produced by the promastigotes. The site of phosphorylation of the extracellular acid phosphatase is not yet known.

摘要

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