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泌乳期山羊半乳切除术后乳腺发育和功能的代偿性变化

Compensatory changes in mammary development and function after hemimastectomy in lactating goats.

作者信息

Knight C H

出版信息

J Reprod Fertil. 1987 Mar;79(2):343-52. doi: 10.1530/jrf.0.0790343.

DOI:10.1530/jrf.0.0790343
PMID:3572869
Abstract

Goats were hemimastectomized during Weeks 5 or 8 of lactation. The milk yield of the remaining gland (the test gland) usually increased in a compensatory fashion after the operation, although the degree of response varied from no response to a 50% increase. The glands of those goats that responded and received no further treatment maintained an increased milk yield for the duration of the lactation. Changes in the size and composition of the gland were investigated by a combination of udder volume and biopsy in some goats. Increases in both gross size and total DNA content (DNAt, a measure of cell number) were observed in all of these, although the timing of the response varied between individuals. Overall, cell population size was maintained for at least 18 weeks after hemimastectomy whereas in control (unoperated) goats DNAt decreased by 35% over a similar period.

摘要

在泌乳第5周或第8周对山羊进行半乳房切除术。手术后,剩余腺体(试验腺体)的产奶量通常会以代偿性方式增加,尽管反应程度各不相同,从无反应到增加50%不等。那些有反应且未接受进一步治疗的山羊的腺体,在整个泌乳期内产奶量都保持增加。在一些山羊中,通过乳房体积测量和活检相结合的方法研究了腺体大小和组成的变化。在所有这些山羊中,均观察到总体大小和总DNA含量(DNAt,细胞数量的一种衡量指标)增加,尽管个体之间反应的时间有所不同。总体而言,半乳房切除术后细胞群体大小至少维持18周,而在对照(未手术)山羊中,类似时间段内DNAt下降了35%。

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