Hiram C. Polk, Jr MD Department of Surgery, Price Institute of Surgical Research, University of Louisville, Louisville, KY, 40292, USA.
Division of Colon & Rectal Surgery, Hiram C. Polk Jr MD Department of Surgery, University of Louisville, 550 South Jackson St, Louisville, KY, 40202, USA.
Langenbecks Arch Surg. 2022 Nov;407(7):2595-2605. doi: 10.1007/s00423-022-02572-y. Epub 2022 Jun 22.
Despite advances in medical therapy, surgery continues to play a vital role in the management of Crohn's disease and its complications. Continuing from Part I of this series (small intestine/ileal disease), we focus next on colonic Crohn's disease and associated neoplasms. We will first review the surgical management of medical-refractory Crohn's colitis and its complications and then examine cancer risk, surveillance, and surgical management of Crohn's-associated colorectal dysplasia and malignancy. We conclude with a discussion of restoration of gastrointestinal continuity following colonic surgery for Crohn's disease.
尽管医学治疗取得了进步，但手术在克罗恩病及其并发症的治疗中仍然起着至关重要的作用。本系列文章（小肠/回肠疾病）的上篇（Part I）介绍了回肠克罗恩病及其相关病变，本篇（Part II）将重点介绍结肠克罗恩病及其相关肿瘤。我们将首先回顾药物难治性克罗恩病性结肠炎及其并发症的手术治疗，然后探讨克罗恩病相关结直肠异型增生和恶性肿瘤的癌变风险、监测和手术治疗。最后，我们将讨论克罗恩病结肠切除术后胃肠道连续性的恢复。
