Emerg Infect Dis. 2022 Jul;28(7):1466-1470. doi: 10.3201/eid2807.212315.
We report a case of Anncaliia algerae microsporidia infection in an immunosuppressed kidney transplant recipient in China. Light microscopy and transmission electron microscopy initially failed to identify A. algerae, which eventually was detected by metagenomic next-generation sequencing. Our case highlights the supporting role of metagenomic sequencing in early identification of uncommon pathogens.
我们报告了一例中国免疫抑制肾移植受者感染安卡利娅阿尔盖耳微孢子虫的病例。光镜和透射电镜最初未能鉴定出安卡利娅阿尔盖耳微孢子虫,最终通过宏基因组下一代测序检测出来。我们的病例强调了宏基因组测序在早期鉴定罕见病原体中的辅助作用。