Department of Pathology, Wayne State University, Detroit, MI, USA.
Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
J Assist Reprod Genet. 2022 Sep;39(9):1987-1991. doi: 10.1007/s10815-022-02554-5. Epub 2022 Jun 22.
The use of platelet-rich plasma is being investigated in reproductive medicine and clinically promoted as a fertility treatment for menopause. We aimed to review the literature on the impact of PRP on fertility in menopause.
A literature search was performed using the PubMed and MEDLINE search engines. The search was limited to the English language. Articles studying PRP use in menopause were selected for the purpose of this review.
Limited case reports and case series studied fertility outcomes of PRP in menopause. Randomized controlled trials are lacking. Furthermore, no studies have been conducted to evaluate the effect of different PRP concentrations, injection techniques, or side effects on reproductive outcomes in menopausal women.
There is a dearth of data to support the routine implementation of intraovarian PRP injections for fertility restoration in menopausal women. Patients considering such therapy need to be well aware of the lack of adequate data for PRP use in menopause and should be counseled accordingly.
富血小板血浆（PRP）在生殖医学中的应用正在得到研究，并在临床上被推广为治疗更年期的生育疗法。我们旨在综述 PRP 对更年期生育力影响的相关文献。
使用 PubMed 和 MEDLINE 搜索引擎进行文献检索。检索仅限于英文文献。选择研究 PRP 在更年期应用的文章进行本综述。
有限的病例报告和病例系列研究了 PRP 在更年期的生育结局。缺乏随机对照试验。此外，尚无研究评估不同 PRP 浓度、注射技术或副作用对更年期妇女生殖结局的影响。
缺乏数据支持常规实施卵巢内 PRP 注射以恢复更年期妇女的生育能力。考虑此类治疗的患者需要充分了解 PRP 在更年期应用缺乏足够数据的情况，并相应地进行咨询。
