College of Environment and Resources, Zhejiang University of Technology, Hangzhou, 310032, Zhejiang, China.
College of Environmental and Resource Sciences, Zhejiang University, Hangzhou, 310058, Zhejiang, China.
Environ Sci Pollut Res Int. 2022 Nov;29(54):81222-81233. doi: 10.1007/s11356-022-21267-x. Epub 2022 Jun 22.
Secondary metabolism, which helps a plant cope with external stress, is sensitive to environmental changes and plays a prominent role in maintaining plant health. However, few studies of the effects of tetracycline on the relationships between secondary metabolism and plant stress responses have been performed. Here, secondary metabolism, nutritional value, and oxidative stress responses in oilseed rape (Brassica napus L.) exposed to tetracycline for 14 days were investigated. Tetracycline inhibited growth and biomass accumulation and decreased the chlorophyll content. The sinapine, phenol, and flavonoid contents were 118.46%, 99.67%, and 93.07% higher, respectively, but the carotenoid content was 76.47% lower in plants exposed to 8 mg/L tetracycline than the control plants. Tetracycline affected the nutritional value of oilseed rape. Tetracycline decreased the dietary fiber, soluble sugar contents, and microelement (Fe, Mn, and Zn) contents. The antioxidant system also responded strongly to tetracycline. The catalase and peroxidase activities were increased and the superoxide dismutase activity was decreased by tetracycline. Tetracycline caused oxidative damage and secondary metabolite disturbances and adversely affected oilseed rape growth and quality. The results provide a new perspective on the effects of tetracycline on plants in relation to secondary metabolites and improve our understanding involved in the toxicity of tetracycline.
次生代谢有助于植物应对外部压力，对环境变化敏感，在维持植物健康方面发挥着重要作用。然而，关于四环素对次生代谢与植物应激反应之间关系的影响的研究很少。在这里，研究了四环素暴露 14 天后油菜（Brassica napus L.）的次生代谢、营养价值和氧化应激反应。四环素抑制生长和生物量积累，并降低叶绿素含量。与对照植物相比，暴露于 8mg/L 四环素的植物中的芥子碱、酚类和类黄酮含量分别增加了 118.46%、99.67%和 93.07%，而类胡萝卜素含量降低了 76.47%。四环素影响油菜的营养价值。四环素降低了膳食纤维、可溶性糖含量和微量元素（Fe、Mn 和 Zn）含量。抗氧化系统也对四环素有强烈的反应。四环素增加了过氧化氢酶和过氧化物酶的活性，降低了超氧化物歧化酶的活性。四环素导致氧化损伤和次生代谢物紊乱，对油菜的生长和品质产生不利影响。这些结果为四环素对植物次生代谢物的影响提供了新的视角，并提高了我们对四环素毒性的认识。
