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全麻无肌松下氯丙嗪治疗术中呃逆 1 例报告

Effective Treatment of Intraoperative Hiccups With Chlorpromazine Under General Anesthesia Without Muscle Relaxants: A Case Report.

机构信息

From the Department of Health Services Research, University of Tsukuba, Ibaraki, Japan.

Department of Anesthesiology, Tsuchiura Kyodo General Hospital, Ibaraki, Japan.

出版信息

A A Pract. 2022 Jun 20;16(6):e01597. doi: 10.1213/XAA.0000000000001597. eCollection 2022 Jun 1.

DOI:10.1213/XAA.0000000000001597
PMID:35732020
Abstract

Hiccups are common reflexes and many treatment methods have been reported. Chlorpromazine is a known treatment option for hiccups, but its efficacy under general anesthesia remains unclear. We report the case of a patient with vagal schwannoma who developed hiccups while under general anesthesia. Muscle relaxants were not used because the patient was under neuromonitoring. The depth of anesthesia was deepened; however, the hiccups did not disappear. The hiccups were relieved by intravenous chlorpromazine administration (total; 5 mg), which allowed for surgery under neuromonitoring. This case indicates that chlorpromazine may be effective to treat hiccups under general anesthesia.

摘要

打嗝是常见的反射现象,已有多种治疗方法被报道。氯丙嗪是一种已知的打嗝治疗选择,但它在全身麻醉下的疗效尚不清楚。我们报告了一例在全身麻醉下出现打嗝的副神经节瘤患者。由于患者正在进行神经监测,因此未使用肌肉松弛剂。尽管加深了麻醉深度,但打嗝并未消失。静脉注射氯丙嗪(总量 5mg)缓解了打嗝,从而可以在神经监测下进行手术。本病例表明,氯丙嗪可能对全身麻醉下的打嗝有效。

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Front Neurol. 2025 Aug 13;16:1615318. doi: 10.3389/fneur.2025.1615318. eCollection 2025.
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Pathogenesis and treatment of perioperative hiccups: a narrative review.围手术期呃逆的发病机制与治疗:一项叙述性综述
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Treatment-resistant hiccups during general anesthesia possibly caused by remimazolam: a case report.
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