Department of Medicine, Michigan State University, East Lansing, Michigan, USA
Department of Medicine, Michigan State University, East Lansing, Michigan, USA.
BMJ Case Rep. 2022 Jun 22;15(6):e249871. doi: 10.1136/bcr-2022-249871.
A man in his 60s with stage 3 squamous cell carcinoma of the left lung status postchemotherapy and radiation therapy presented with mixed septic and obstructive shock with multiorgan dysfunction. Initial electrocardiogram showed sinus tachycardia and diffuse concaved ST elevation. Transthoracic echocardiogram revealed pericardial effusion with tamponade physiology. CT thorax was notable for dense left lung consolidation with pleural effusion. Emergent pericardiocentesis and percutaneous balloon pericardiotomy were performed which successfully drained 500 mL of purulent pericardial fluid. A left chest tube was placed and revealed a large volume of empyema. Both pericardial and pleural fluid cultures yielded similar strains of The patient was initially treated with empiric broad-spectrum intravenous antibiotics which were eventually de-escalated to intravenous ceftriaxone based on microbiology culture and sensitivity. Unfortunately, the patient developed pulseless electrical activity arrest on day 10 of intensive care unit stay and expired despite cardiopulmonary resuscitation.
一位 60 多岁的男性,患有左肺 3 期鳞状细胞癌,曾接受化疗和放疗,因混合性脓毒性和阻塞性休克伴多器官功能障碍而就诊。初始心电图显示窦性心动过速和弥漫性凹面 ST 段抬高。经胸超声心动图显示有心包积液伴填塞生理学。胸部 CT 显示左肺实变伴胸腔积液。紧急进行了心包穿刺和经皮气囊心包切开术,成功抽出 500 毫升脓性心包积液。放置了左侧胸腔引流管,发现大量积脓。心包和胸腔积液培养均培养出相同的菌株。患者最初接受经验性广谱静脉内抗生素治疗,根据微生物学培养和药敏试验,最终降级为静脉内头孢曲松。不幸的是,患者在重症监护病房入住第 10 天出现无脉性电活动骤停,尽管进行了心肺复苏,仍死亡。