Asakawa H, Ohtake S, Koyama K, Otawa H
Gan No Rinsho. 1987 Apr;33(4):361-4.
Seventeen 5-year survivors, treated with a combination of radiation and chemotherapy, were followed up from 5 to 10 years. Out of them, 10 cases died within 10 years after the completion of radiotherapy. Late local recurrence and remote metastasis of esophageal cancer were observed in 3 cases, and other malignancies of the stomach, lung and esophagus were found in 3 other cases. Furthermore, the cause of death was late radiation injuries (radiation myelopathy and pulmonary fibrosis) in 2 cases and intercurrent disease in 2 others. Dysphagia due to cicatricial structure of the esophagus occurred in 5 cases.
17例接受放疗和化疗联合治疗的5年幸存者，随访时间为5至10年。其中，10例在放疗结束后10年内死亡。3例出现食管癌局部晚期复发和远处转移，另外3例发现胃、肺和食管的其他恶性肿瘤。此外，2例死于晚期放射损伤（放射性脊髓病和肺纤维化），另外2例死于并发疾病。5例因食管瘢痕结构导致吞咽困难。
