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具有非典型肿块样表现的变应性支气管肺曲霉病

Allergic Bronchopulmonary Aspergillosis with an Atypical Mass-Like Presentation.

作者信息

Mahmoud Mahmoud Ibrahim, Elfaki Alaeldin, Alhaj Ziad A, Said Abir Hamad

机构信息

Imam Abdulrahman Bin Faisal University, King Fahd Hospital of the University, Respiratory Medicine Unit, Al Khobar, Saudi Arabia.

出版信息

Case Rep Pulmonol. 2022 Jun 13;2022:3627202. doi: 10.1155/2022/3627202. eCollection 2022.

Abstract

Allergic bronchopulmonary aspergillosis is an uncommon condition characterized by airway hypersensitivity to Aspergillus fumigatus, resulting in worsening asthma control and bronchiectasis progression. It is associated with various radiological features. Here, we describe a 53-year-old lady with atypical CT chest finding as soft tissue density masses in both lungs evaluated initially as a lung tumour. The diagnosis was particularly challenging given the history of undiagnosed asthma. Nevertheless, bronchoscopy findings of mucus impaction and blood eosinophilia redirect the clinical thinking toward ABPA. Laboratory examination showed elevated total IgE, Aspergillus fumigatus IgE, and Aspergillus niger IgE. Shortly after treatments with systemic steroids, our patient showed a symptomatic improvement. Moreover, subsequent follow-up showed a resolution of the radiological opacities.

摘要

变应性支气管肺曲霉病是一种罕见疾病,其特征为气道对烟曲霉过敏,导致哮喘控制恶化和支气管扩张进展。它与多种影像学特征相关。在此,我们描述一位53岁女性,其胸部CT有非典型表现,双肺出现软组织密度肿块,最初被评估为肺部肿瘤。鉴于未确诊哮喘的病史,诊断颇具挑战性。然而,支气管镜检查发现黏液嵌塞和血液嗜酸性粒细胞增多,使临床思路转向变应性支气管肺曲霉病。实验室检查显示总IgE、烟曲霉IgE和黑曲霉IgE升高。在接受全身类固醇治疗后不久,我们的患者症状有所改善。此外,后续随访显示影像学上的不透明影消失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4457/9208993/c3a836dd9653/CRIPU2022-3627202.001.jpg

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