Kishimoto Y, Yamamoto T, Kato S, Wakushima T, Hirayama C
Jpn J Med. 1987 Feb;26(1):41-5. doi: 10.2169/internalmedicine1962.26.41.
Gonadal function in male patients with various liver disease has been evaluated by basal plasma testosterone level and a response of plasma testosterone to human chorionic gonadotropin. Compared with healthy male subjects of similar age, gonadal function was not reduced in chronic hepatitis, but in alcoholic liver disease without cirrhosis and in alcoholic and non-alcoholic cirrhosis. Gonadal dysfunction in patients with chronic hepatitis and cirrhosis was correlated with abnormal liver tests. It may be concluded that gonadal function in chronic liver disease is reduced either by alcohol abuse or disturbances of hepatic function and/or hepatic hemodynamics.
通过基础血浆睾酮水平以及血浆睾酮对人绒毛膜促性腺激素的反应，对患有各种肝脏疾病的男性患者的性腺功能进行了评估。与年龄相仿的健康男性受试者相比，慢性肝炎患者的性腺功能并未降低，但在无肝硬化的酒精性肝病以及酒精性和非酒精性肝硬化患者中，性腺功能降低。慢性肝炎和肝硬化患者的性腺功能障碍与肝功能检查异常相关。可以得出结论，慢性肝病患者的性腺功能降低是由酒精滥用或肝功能和/或肝血流动力学紊乱所致。
