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药物性血管炎：噻嗪类药物还是新冠疫苗，究竟是谁之过？一例病例报告及文献综述

Drug-induced vasculitis: Thiazide or the COVID-19 vaccine, which one is guilty? A case report and literature review.

作者信息

Hekmat Manoochehr, Jafari Naeini Sepideh, Abbasi Zahra, Dadkhahfar Sahar

机构信息

Department of cardiovascular surgery, Shahid Modarres Hospital Shahid Beheshti university of medical sciences Tehran Iran.

Cardiovascular research center Shahid Beheshti university of medical sciences Tehran Iran.

出版信息

Clin Case Rep. 2022 Jun 13;10(6):e5978. doi: 10.1002/ccr3.5978. eCollection 2022 Jun.

DOI:10.1002/ccr3.5978
PMID:35734191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9194467/
Abstract

A middle-aged woman with a history of COVID-19 vaccine administration and valve replacement surgery was admitted with bilateral palpable purpuric lesions in the lower extremities and headache. Based on the initial diagnosis of vasculitis, corticosteroid therapy was initiated, which led to the resolution of skin lesions.

摘要

一名有新冠病毒疫苗接种史和瓣膜置换手术史的中年女性因双下肢可触及的紫癜性病变和头痛入院。基于血管炎的初步诊断，开始使用皮质类固醇治疗，这使得皮肤病变消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/7ca725fafcf8/CCR3-10-e5978-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/a2a24b157604/CCR3-10-e5978-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/2561c4b64137/CCR3-10-e5978-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/7ca725fafcf8/CCR3-10-e5978-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/a2a24b157604/CCR3-10-e5978-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/2561c4b64137/CCR3-10-e5978-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9194467/7ca725fafcf8/CCR3-10-e5978-g004.jpg

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本文引用的文献

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Glomerulopathies after vaccination against COVID-19. Four cases with three different vaccines in Argentina.接种新冠疫苗后出现的肾小球病。阿根廷4例使用三种不同疫苗的病例。
Nefrologia. 2021 Sep 25. doi: 10.1016/j.nefro.2021.09.003.
2
Images in Vascular Medicine: Leukocytoclastic vasculitis after COVID-19 vaccine booster.血管医学影像：新冠疫苗加强针接种后发生的白细胞破碎性血管炎
Vasc Med. 2022 Feb;27(1):100-101. doi: 10.1177/1358863X211055507. Epub 2021 Nov 1.
3
Possible case of mRNA COVID-19 vaccine-induced small-vessel vasculitis.新冠 mRNA 疫苗诱发小血管血管炎的可能病例。
J Cosmet Dermatol. 2022 Jan;21(1):51-53. doi: 10.1111/jocd.14568. Epub 2021 Oct 27.
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Sinovac COVID-19 vaccine-induced cutaneous leukocytoclastic vasculitis.科兴新冠疫苗诱发的皮肤白细胞破碎性血管炎。
JAAD Case Rep. 2021 Dec;18:1-3. doi: 10.1016/j.jdcr.2021.10.002. Epub 2021 Oct 9.
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Cutaneous vasculitis following COVID-19 vaccination.新冠病毒疫苗接种后发生的皮肤血管炎。
Lancet Rheumatol. 2021 Nov;3(11):e743-e744. doi: 10.1016/S2665-9913(21)00309-X. Epub 2021 Sep 30.
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First description of immune complex vasculitis after COVID-19 vaccination with BNT162b2: a case report.首例 BNT162b2 疫苗接种后 COVID-19 相关免疫复合物性血管炎：病例报告。
BMC Infect Dis. 2021 Sep 16;21(1):958. doi: 10.1186/s12879-021-06655-x.
7
Educational Case: Hypersensitivity Vasculitis.教学案例：过敏性血管炎
Acad Pathol. 2021 Aug 9;8:23742895211030650. doi: 10.1177/23742895211030650. eCollection 2021 Jan-Dec.
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ANCA-Associated Vasculitis Following Pfizer-BioNTech COVID-19 Vaccine.辉瑞-BioNTech COVID-19 疫苗接种后与抗中性粒细胞胞浆抗体相关的血管炎。
Am J Kidney Dis. 2021 Oct;78(4):611-613. doi: 10.1053/j.ajkd.2021.06.016. Epub 2021 Jul 17.
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Asymmetrical cutaneous vasculitis following COVID-19 vaccination with unusual eosinophil preponderance.新型冠状病毒肺炎疫苗接种后出现的不对称性皮肤血管炎，伴有异常的嗜酸性粒细胞增多。
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